Product Name
GH2, cDNA Clone
Full Product Name
GH2 cDNA Clone
Product Gene Name
GH2 cdna clone
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggctgcag gctcccggac gtccctgctc ctggcttttg gcctgctctg cctgtcctgg cttcaagagg gcagtgcctt cccaaccatt cccttatcca ggctttttga caacgctatg ctccgcgccc gtcgcctgta ccagctggca tatgacacct atcaggagtt tgaagaagcc tatatcctga aggagcagaa gtattcattc ctgcagaacc cccagacctc cctctgcttc tcagagtcta ttccaacacc ttccaacagg gtgaaaacgc agcagaaatc taacctagag ctgctccgca tctccctgct gctcatccag tcatggctgg agcccgtgca gctcctcagg agcgtcttcg ccaacagcct ggtgtatggc gcctcggaca gcaacgtcta tcgccacctg aaggacctag aggaaggcat ccaaacgctg atgtggaggc tggaagatgg cagcccccgg actgggcaga tcttcaatca gtcctacagc aagtttgaca caaaatcgca caacgatgac gcactgctca agaactacgg gctgctctac tgcttcagga aggacatgga caaggtcgag acattcctgc gcatcgtgca gtgccgctct gtggagggca gctgtggctt ctag
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of GH2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for GH2. It may not necessarily be applicable to this product.
NCBI Accession #
BC020760
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UniProt Secondary Accession #
O14643; O14644; P09587; B1A4H5; B1A4H7[Other Products]
UniProt Related Accession #
P01242[Other Products]
Molecular Weight
27,101 Da
NCBI Official Full Name
Homo sapiens growth hormone 2, mRNA
NCBI Official Synonym Full Names
growth hormone 2
NCBI Official Symbol
GH2 [Similar Products]
NCBI Official Synonym Symbols
GHL; GHV; GH-V; GHB2; hGH-V
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NCBI Protein Information
growth hormone variant
UniProt Protein Name
Growth hormone variant
UniProt Synonym Protein Names
Growth hormone 2; Placenta-specific growth hormone
Protein Family
Growth hormone
UniProt Gene Name
GH2 [Similar Products]
UniProt Synonym Gene Names
GH-V [Similar Products]
UniProt Entry Name
SOM2_HUMAN
NCBI Summary for GH2
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. As in the case of its pituitary counterpart, growth hormone 1, the predominant isoform of this particular family member shows similar somatogenic activity, with reduced lactogenic activity. Mutations in this gene lead to placental growth hormone/lactogen deficiency. [provided by RefSeq, Jul 2008]
UniProt Comments for GH2
GH2: Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Belongs to the somatotropin/prolactin family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 17q24.2
Cellular Component: extracellular region
Research Articles on GH2
1. genetic association studies in populations in Estonia, Czech Republic, and Bashkortostan/Russia: Data suggest an SNP in GH2 (rs2006123) is associated with ***** height (not body mass index); A-allele is associated with taller stature. [META-ANALYSIS]
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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