Full Product Name
Mouse monoclonal A1AT antibody
Product Synonym Names
A1AT antibody
Product Gene Name
anti-A1AT antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P01009
Specificity
A1AT antibody recognizes recombinant A1AT
Form/Format
Supplied in citrate-tris-HCl buffer, pH 7.0 with 0.02% Proclin 300
Concentration
1 mg/ml (lot specific)
Immunogen
A1AT antibody was raised in Mouse using a synthetic peptide (KLH-coupled) corresponding to the residues of A1AT protein as the immunogen
Preparation and Storage
Store at -20 degree C for 1 year, store at 2-8 degree C for up to 1 month.
Other Notes
Small volumes of anti-A1AT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-A1AT antibody
Proteases; Inhibitors; & Enzymes
Applications Tested/Suitable for anti-A1AT antibody
ELISA (EIA), Western Blot (WB)
Western Blot (WB) of anti-A1AT antibody
Western blot (1:1000) analysis of recombinant protein A1AT with A1AT antibody
NCBI/Uniprot data below describe general gene information for A1AT. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001121179.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001127707.1
[Other Products]
UniProt Primary Accession #
P01009
[Other Products]
UniProt Secondary Accession #
Q0PVP5; Q13672; Q53XB8; Q5U0M1; Q7M4R2; Q86U18; Q86U19; Q96BF9; Q96ES1; A6PX14; B2RDQ8[Other Products]
UniProt Related Accession #
P01009[Other Products]
Molecular Weight
34,755 Da
NCBI Official Full Name
alpha-1-antitrypsin
NCBI Official Synonym Full Names
serpin family A member 1
NCBI Official Symbol
SERPINA1 [Similar Products]
NCBI Official Synonym Symbols
PI; A1A; AAT; PI1; A1AT; PRO2275; alpha1AT
[Similar Products]
NCBI Protein Information
alpha-1-antitrypsin
UniProt Protein Name
Alpha-1-antitrypsin
UniProt Synonym Protein Names
Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1
UniProt Gene Name
SERPINA1 [Similar Products]
UniProt Synonym Gene Names
AAT; PI; SPAAT [Similar Products]
NCBI Summary for A1AT
The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for A1AT
Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.
Research Articles on A1AT
1. The Alpha-1 antitrypsin (A1AT) deficiency (A1ATD) is a genetic autosomal recessive disease, characterized by low serum levels of A1AT.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
