Full Product Name
Mouse monoclonal AF10 antibody
Product Synonym Names
AF10 antibody
Product Gene Name
anti-AF10 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clone Number
HAF10 10D3/8
Purity/Purification
Purified by affinity chromatography
Form/Format
Supplied as liquid in PBS with 0.02% sodium azide
Concentration
1 mg/ml (lot specific)
Immunogen
AF10 antibody was raised in Mouse using purified AF10 as the immunogen
Preparation and Storage
Store as concentrated solution. Aliquot and store at -20 degree C or below. Avoid repeated freeze-thaw cycles.
Other Notes
Small volumes of anti-AF10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-AF10 antibody
DNA & RNA
Applications Tested/Suitable for anti-AF10 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for AF10. It may not necessarily be applicable to this product.
NCBI Accession #
AAT47519.1
[Other Products]
UniProt Secondary Accession #
Q5JT37; Q5VX90; Q66K63; B1ANA8[Other Products]
Molecular Weight
20,047 Da
NCBI Official Full Name
AF10
UniProt Protein Name
Protein AF-10
UniProt Synonym Protein Names
ALL1-fused gene from chromosome 10 protein
UniProt Gene Name
MLLT10 [Similar Products]
UniProt Synonym Gene Names
AF10 [Similar Products]
UniProt Comments for AF10
MLLT10: Probably involved in transcriptional regulation. In vitro or as fusion protein with MLL has transactivation activity. Binds to cruciform DNA. A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10;11)(p12;q23) with MLL/HRX. The result is a rogue activator protein. A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10;11)(p13;q14) with PICALM. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Oncoprotein; Transcription factor
Chromosomal Location of Human Ortholog: 10p12.31
Cellular Component: cytoplasm; nucleoplasm; nucleus; protein complex
Molecular Function: protein binding
Biological Process: positive regulation of transcription from RNA polymerase II promoter
Disease: Leukemia, Acute Myeloid
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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