2',5'-Oligoadenylate Synthetase, Polyclonal Antibody

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

The antibody is a rabbit polyclonal antibody raised against OASL. It has beenselected for its ability to recognize OASL in immunohistochemical staining andwestern blotting.

Affinity Chromatography

Liquid

200ug/ml (lot specific)

Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Small volumes of anti-OASL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)

Western blotting: 0.2-2ug/mL;1:250-2500
Immunohistochemistry: 5-20ug/mL;1:25-100
Immunocytochemistry: 5-20ug/mL;1:25-100
Optimal working dilutions must be determined by end user.

Western Blot: Sample: Recombinant protein.

DABstainingonIHC-P.Samples:HumanTissue)

43,942 Da

2'-5'-oligoadenylate synthetase like

2'-5'-oligoadenylate synthase-like protein

2'-5'-oligoadenylate synthase-like protein

TRIP14; 2'-5'-OAS-RP; TR-interacting protein 14; TRIP-14; p59OASL  [Similar Products]

OASL: a protein of the 2'-5'-oligoadenylate synthetase family, but does not have 2'-5'-OAS activity. Binds double-stranded RNA and DNA. Interacts with the ligand binding domain of the thyroid receptor (TR). Does not require the presence of thyroid hormone for its interaction. Contains a ubiquitin-like domain that interacts with methyl CpG-binding protein 1.

Protein type: DNA-binding; Nucleolus

Chromosomal Location of Human Ortholog: 12q24.31

Cellular Component: cytoplasm; cytosol; membrane; nucleolus; nucleoplasm

Molecular Function: 2'-5'-oligoadenylate synthetase activity; ATP binding; DNA binding; double-stranded RNA binding; RNA binding; thyroid hormone receptor binding

Biological Process: defense response to virus; negative regulation of viral genome replication; response to virus

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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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