Product Name
SGLT1, Polyclonal Antibody
Popular Item
Full Product Name
Anti-SGLT1 Antibody
Product Synonym Names
NAGT; SGLT1; Sodium/glucose cotransporter 1; Na(+)/glucose cotransporter 1; High affinity sodium-glucose cotransporter; Solute carrier family 5 member 1
Product Gene Name
anti-SGLT1 antibody
[Similar Products]
Product Synonym Gene Name
SLC5A1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P13866
Species Reactivity
Human, Mouse
Specificity
Recognizes endogenous levels of SGLT1 protein.
Purity/Purification
The antibody was Purified by immunogen affinity chromatography
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Immunogen
KLH-conjugated synthetic peptide of human SGLT1
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-SGLT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SGLT1 antibody
Rabbit polyclonal antibody to SGLT1
Applications Tested/Suitable for anti-SGLT1 antibody
Western Blot (WB)
Application Notes for anti-SGLT1 antibody
WB: 1/500 - 1/2000
Western Blot (WB) of anti-SGLT1 antibody
Western blot analysis of SGLT1 expression in HepG2 (A), mouse kidney (B), mouse brain (C) whole cell lysates.

NCBI/Uniprot data below describe general gene information for SGLT1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000334.1
[Other Products]
NCBI GenBank Nucleotide #
NM_000343.3
[Other Products]
UniProt Primary Accession #
P13866
[Other Products]
UniProt Secondary Accession #
B2R7E2; B7Z4Q9; B7ZA69[Other Products]
UniProt Related Accession #
P13866[Other Products]
Molecular Weight
60,097 Da
NCBI Official Full Name
sodium/glucose cotransporter 1 isoform 1
NCBI Official Synonym Full Names
solute carrier family 5 member 1
NCBI Official Symbol
SLC5A1 [Similar Products]
NCBI Official Synonym Symbols
NAGT; SGLT1; D22S675
[Similar Products]
NCBI Protein Information
sodium/glucose cotransporter 1
UniProt Protein Name
Sodium/glucose cotransporter 1
UniProt Synonym Protein Names
High affinity sodium-glucose cotransporter; Solute carrier family 5 member 1
UniProt Gene Name
SLC5A1 [Similar Products]
UniProt Synonym Gene Names
NAGT; SGLT1; Na(+)/glucose cotransporter 1 [Similar Products]
NCBI Summary for SGLT1
This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
UniProt Comments for SGLT1
Actively transports glucose into cells by Na+ cotransport with a Na+ to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na+/glucose cotransporter arranged in series along kidney proximal tubules.
Research Articles on SGLT1
1. Duodenal SGLT-1 expression is increased in individuals with 1-hour postload hyperglycemia or impaired glucose tolerance, as well as in subjects with T2 Diabetes mellitus, and it positively correlates with early postload glucose excursion.
Precautions
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Disclaimer
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