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IL9R, Polyclonal Antibody

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产品名称: IL9R, Polyclonal Antibody
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简单介绍

IL9R, Polyclonal Antibody


IL9R, Polyclonal Antibody  的详细介绍
Product Name

IL9R, Polyclonal Antibody

Full Product Name

IL9R, ID (IL9R, Interleukin-9 receptor, CD129)

Product Synonym Names
Anti -IL9R, ID (IL9R, Interleukin-9 receptor, CD129)
Product Gene Name

anti-IL9R antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Chromosome Location
Chromosome: Y; NC_000024.9 (59330252..59343488). Location: Xq28 and Yq12
OMIM
300007
3D Structure
ModBase 3D Structure for Q01113
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Specificity
Human, mouse
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Immunogen
IL9R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-199 amino acids from the Central region of human IL9R.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-IL9R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-IL9R antibody
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.
Product Categories/Family for anti-IL9R antibody
Antibodies; Abs to CD Markers
Applications Tested/Suitable for anti-IL9R antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-IL9R antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50
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NCBI/Uniprot data below describe general gene information for IL9R. It may not necessarily be applicable to this product.
NCBI GI #
29171682
NCBI GeneID
3581
NCBI Accession #
NP_002177.2 [Other Products]
NCBI GenBank Nucleotide #
NM_002186.2 [Other Products]
UniProt Primary Accession #
Q01113 [Other Products]
UniProt Secondary Accession #
Q14634; Q8WWU1; Q96TF0; B9ZVT0[Other Products]
UniProt Related Accession #
Q01113[Other Products]
Molecular Weight
57,147 Da[Similar Products]
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NCBI Official Full Name
interleukin-9 receptor isoform 1
NCBI Official Synonym Full Names
interleukin 9 receptor
NCBI Official Symbol
IL9R  [Similar Products]
NCBI Official Synonym Symbols
CD129; IL-9R
  [Similar Products]
NCBI Protein Information
interleukin-9 receptor; IL-9 receptor
UniProt Protein Name
Interleukin-9 receptor
Protein Family
Interleukin-9 receptor
UniProt Gene Name
IL9R  [Similar Products]
UniProt Synonym Gene Names
IL-9 receptor; IL-9R  [Similar Products]
UniProt Entry Name
IL9R_HUMAN
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NCBI Summary for IL9R
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for IL9R
IL9R: This is a receptor for interleukin-9. Belongs to the type I cytokine receptor family. Type 4 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, cytokine; Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq28 and Yq12

Cellular Component: extracellular space; integral to plasma membrane

Molecular Function: interleukin-9 binding; interleukin-9 receptor activity

Biological Process: cell proliferation; signal transduction; positive regulation of cell growth
Research Articles on IL9R
1. One of the identified peptide sequences corresponded to a fragment of the human interleukin-9 receptor alpha (IL-9Ralpha).
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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