Product Name
CANT1, Blocking Peptide
Full Product Name
CANT1 Peptide - middle region
Product Gene Name
CANT1 blocking peptide
[Similar Products]
Product Synonym Gene Name
SCAN-1; SHAPY; DBQD; SCAN1[Similar Products]
CANT1 peptide (MBS3235849) is used for blocking the activity of CANT1 antibody (MBS3210896)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8WVQ1
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of CANT1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CANT1 blocking peptide
This is a synthetic peptide designed for use in combination with anti-CANT1 antibody made
Target Description: CANT1 belongs to the apyrase family.It is a calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. The enzyme has very low activity towards ADP and even lower activity towards ATP. And it does not hydrolyze AMP and GMP.
Product Categories/Family for CANT1 blocking peptide
Peptide
Applications Tested/Suitable for CANT1 blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for CANT1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_620148
[Other Products]
NCBI GenBank Nucleotide #
NM_138793
[Other Products]
UniProt Primary Accession #
Q8WVQ1
[Other Products]
UniProt Related Accession #
Q8WVQ1[Other Products]
NCBI Official Full Name
soluble calcium-activated nucleotidase 1
NCBI Official Synonym Full Names
calcium activated nucleotidase 1
NCBI Official Symbol
CANT1 [Similar Products]
NCBI Official Synonym Symbols
DBQD; EDM7; DBQD1; SCAN1; SHAPY; SCAN-1
[Similar Products]
NCBI Protein Information
soluble calcium-activated nucleotidase 1
UniProt Protein Name
Soluble calcium-activated nucleotidase 1
UniProt Synonym Protein Names
Apyrase homolog; Putative MAPK-activating protein PM09; Putative NF-kappa-B-activating protein 107
Protein Family
Soluble calcium-activated nucleotidase
UniProt Gene Name
CANT1 [Similar Products]
UniProt Synonym Gene Names
SHAPY; SCAN-1 [Similar Products]
UniProt Entry Name
CANT1_HUMAN
NCBI Summary for CANT1
This protein encoded by this gene belongs to the apyrase family. It functions as a calcium-dependent nucleotidase with a preference for UDP. Mutations in this gene are associated with Desbuquois dysplasia with hand anomalies. Alternatively spliced transcript variants have been noted for this gene.[provided by RefSeq, Mar 2010]
UniProt Comments for CANT1
CANT1: Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP. Involved in proteoglycan synthesis. Defects in CANT1 are the cause of Desbuquois dysplasia (DBQD). A chondrodysplasia characterized by severe prenatal and postnatal growth retardation (less than -5 SD), joint laxity, short extremities, progressive scoliosis, round face, midface hypoplasia, prominent bulging eyes. The main radiologic features are short long bones with metaphyseal splay, a 'Swedish key' appearance of the proximal femur (exaggerated trochanter), and advance carpal and tarsal bone age. Two forms of Desbuquois dysplasia are distinguished on the basis of the presence (type 1) or absence (type 2) of characteristic hand anomalies: an extra ossification center distal to the second metacarpal, delta phalanx, bifid distal thumb phalanx, and phalangeal dislocations. Belongs to the apyrase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Hydrolase; Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; Endoplasmic reticulum; Membrane protein, integral; EC 3.6.1.6
Chromosomal Location of Human Ortholog: 17q25.3
Cellular Component: endoplasmic reticulum membrane; integral to membrane
Molecular Function: signal transducer activity; calcium ion binding; uridine-diphosphatase activity
Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; proteoglycan biosynthetic process; signal transduction
Disease: Desbuquois Dysplasia 1
Research Articles on CANT1
1. CANT1 long non-coding RNA triggers efficient therapeutic efficacy by correcting aberrant long non-coding cascade in malignant uveal melanoma.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
