Full Product Name
ANF Polyclonal Antibody
Product Synonym Names
Natriuretic peptides A; CDD-ANF; Prepronatriodilatin; Cardiodilatin-related peptide; CDP; Atrial natriuretic factor; ANF; Atrial natriuretic peptide; ANP; NPPA; ANP; PND
Product Gene Name
anti-ANF antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P01160
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-ANF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ANF antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-ANF antibody
WB: 1:500-2000
ELISA: 1:5000-20000
NCBI/Uniprot data below describe general gene information for ANF. It may not necessarily be applicable to this product.
NCBI Accession #
NP_006163.1
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NCBI GenBank Nucleotide #
NM_006172.3
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UniProt Primary Accession #
P01160
[Other Products]
UniProt Secondary Accession #
Q13766; Q5JZE1[Other Products]
UniProt Related Accession #
P01160[Other Products]
NCBI Official Full Name
natriuretic peptides A preproprotein
NCBI Official Synonym Full Names
natriuretic peptide A
NCBI Official Symbol
NPPA [Similar Products]
NCBI Official Synonym Symbols
ANF; ANP; CDD; CDP; PND; ATFB6; ATRST2; CDD-ANF
[Similar Products]
NCBI Protein Information
natriuretic peptides A
UniProt Protein Name
Natriuretic peptides A
UniProt Synonym Protein Names
CDD-ANF; Cardiodilatin; CDD
UniProt Gene Name
NPPA [Similar Products]
UniProt Synonym Gene Names
ANP; PND; CDD; CDP; ANF; ANP [Similar Products]
NCBI Summary for ANF
The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1. [provided by RefSeq, Oct 2015]
UniProt Comments for ANF
Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
Research Articles on ANF
1. An increase in year-by-year BP variability over the past 6 years is associated with elevated plasma levels of ANP and BNP in the Japanese general population.
Precautions
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Disclaimer
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