Product Name
TALDO1, Polyclonal Antibody
Full Product Name
TALDO1 Polyclonal Antibody
Product Synonym Names
TAL; TALH; TAL-H; TALDOR
Product Gene Name
anti-TALDO1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purification
Concentration
1.6mg/ml (lot specific)
Immunogen
Fusion protein of human TALDO1
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-51439 / sc-51440 / sc-134795
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-TALDO1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TALDO1 antibody
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis.
Applications Tested/Suitable for anti-TALDO1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-TALDO1 antibody
ELISA: 1:2000-5000
IHC: 1:25-100
WB: 1:500-2000
Immunohistochemistry (IHC) of anti-TALDO1 antibody
Immunohistochemistry of paraffin-embedded Human prostate cancer using TALDO1 Polyclonal Antibody at dilution of 1/30
Immunohistochemistry (IHC) of anti-TALDO1 antibody
Immunohistochemistry of paraffin-embedded Human liver cancer using TALDO1 Polyclonal Antibody at dilution of 1/30
NCBI/Uniprot data below describe general gene information for TALDO1. It may not necessarily be applicable to this product.
NCBI GenBank Nucleotide #
NM_006755.1
[Other Products]
UniProt Secondary Accession #
O00751; Q8WV32; Q8WZ45; B2R8M2[Other Products]
UniProt Related Accession #
P37837[Other Products]
NCBI Official Full Name
transaldolase
NCBI Official Synonym Full Names
transaldolase 1
NCBI Official Symbol
TALDO1 [Similar Products]
NCBI Official Synonym Symbols
TAL; TALH; TAL-H; TALDOR
[Similar Products]
NCBI Protein Information
transaldolase
UniProt Protein Name
Transaldolase
Protein Family
Transaldolase
UniProt Gene Name
TALDO1 [Similar Products]
UniProt Synonym Gene Names
TAL; TALDO; TALDOR [Similar Products]
UniProt Entry Name
TALDO_HUMAN
NCBI Summary for TALDO1
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008]
UniProt Comments for TALDO1
TALDO1: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. Defects in TALDO1 are the cause of transaldolase 1 deficiency (TALDO1 deficiency). It results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris. Belongs to the transaldolase family. Type 1 subfamily.
Protein type: Carbohydrate Metabolism - pentose phosphate pathway; EC 2.2.1.2; Transferase
Chromosomal Location of Human Ortholog: 11p15.5-p15.4
Cellular Component: cytoplasm; cytosol; nucleus
Molecular Function: protein binding; transaldolase activity
Biological Process: carbohydrate metabolic process; pentose-phosphate shunt; xylulose biosynthetic process
Disease: Transaldolase Deficiency
Research Articles on TALDO1
1. The above findings support the premise that biallelic mutations in TALDO1 are responsible for transaldolase deficiency and confirm the broad phenotypic variability of this condition, even with the same genotype.
Precautions
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Disclaimer
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