Product Name
D-3-phosphoglycerate dehydrogenase (Phgdh), ELISA Kit
Full Product Name
Mouse D-3-phosphoglycerate dehydrogenase ELISA Kit
Product Synonym Names
Mus musculus; Phgdh; D-3-phosphoglycerate dehydrogenase; 3-PGDH; A10; Phgdh; 1.1.1.95
Product Gene Name
Phgdh elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for Q61753
Detection Range
0.312-20 ng/mL
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of Phgdh elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for Phgdh purchase
MBS2881810 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the D-3-phosphoglycerate dehydrogenase (Phgdh) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Phgdh. The ELISA analytical biochemical technique of the MBS2881810 kit is based on Phgdh antibody-Phgdh antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Phgdh antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Phgdh. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for Phgdh. It may not necessarily be applicable to this product.
NCBI Accession #
NP_058662.2
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NCBI GenBank Nucleotide #
NM_016966.3
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UniProt Primary Accession #
Q61753
[Other Products]
UniProt Secondary Accession #
Q3TEE5; Q75SV9; Q8C603[Other Products]
UniProt Related Accession #
Q61753[Other Products]
Molecular Weight
56,586 Da
NCBI Official Full Name
D-3-phosphoglycerate dehydrogenase
NCBI Official Synonym Full Names
3-phosphoglycerate dehydrogenase
NCBI Official Symbol
Phgdh [Similar Products]
NCBI Official Synonym Symbols
A10; PGD; PGAD; PGDH; SERA; 3PGDH; 3-PGDH; 4930479N23
[Similar Products]
NCBI Protein Information
D-3-phosphoglycerate dehydrogenase
UniProt Protein Name
D-3-phosphoglycerate dehydrogenase
UniProt Synonym Protein Names
A10
Protein Family
D-3-phosphoglycerate dehydrogenase
UniProt Gene Name
Phgdh [Similar Products]
UniProt Synonym Gene Names
3-PGDH [Similar Products]
UniProt Entry Name
SERA_MOUSE
UniProt Comments for Phgdh
PHGDH: Defects in PHGDH are the cause of phosphoglycerate dehydrogenase deficiency (PHGDH deficiency). It is characterized by congenital microcephaly, psychomotor retardation, and seizures. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein type: Amino Acid Metabolism - glycine, serine and threonine; Oxidoreductase; EC 1.1.1.95; Cell development/differentiation
Cellular Component: myelin sheath
Molecular Function: NAD binding; oxidoreductase activity; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; phosphoglycerate dehydrogenase activity
Biological Process: amino acid biosynthetic process; gamma-aminobutyric acid metabolic process; glial cell development; glutamine metabolic process; glycine metabolic process; L-serine biosynthetic process; L-serine metabolic process; metabolic process; neural tube development; neurite development; neurogenesis; regulation of gene expression; serine family amino acid biosynthetic process; spinal cord development; taurine metabolic process; threonine metabolic process
Research Articles on Phgdh
1. These results indicate that the PHGDH gene expression, dictated by IL-2R signaling, is a crucial event for DNA synthesis during S phase of activated T cells.
Precautions
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Disclaimer
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