grainyhead-like 2 (Drosophila), ELISA Kit

Mouse Grainyhead-like protein 2 homolog (GRHL2) ELISA kit; BOM; DFNA28; FLJ11172; FLJ13782; MGC149294; MGC149295; TFCP2L3; brother of mammalian grainyhead; transcription factor CP2-like 3; grainyhead-like 2 (Drosophila)

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of GRHL2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9321795 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the grainyhead-like 2 (Drosophila) (GRHL2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GRHL2. The ELISA analytical biochemical technique of the MBS9321795 kit is based on GRHL2 antibody-GRHL2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GRHL2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GRHL2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

71,195 Da

grainyhead-like 2 (Drosophila)

grainyhead-like protein 2 homolog; grainyhead like 2; brother of mammalian grainyhead; transcription factor CP2-like 3

Grainyhead-like protein 2 homolog

Bom; Tcfcp2l3  [Similar Products]

GRHL2_MOUSE

GRHL2: May function as a transcription factor. Defects in GRHL2 are the cause of deafness autosomal dominant type 28 (DFNA28). DFNA28 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. DFNA28 is characterized by mild to moderate hearing loss across most frequencies that progressed to severe loss in the higher frequencies by the fifth decade. Age at onset varied, with the earliest case documented at 7 years of age. Belongs to the grh/CP2 family. Grainyhead subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor

Cellular Component: membrane; intercellular junction; nucleus

Molecular Function: DNA binding; chromatin DNA binding; sequence-specific DNA binding; transcription factor activity

Biological Process: neural tube development; epidermis development; camera-type eye development; transcription, DNA-dependent; in utero embryonic development; respiratory tube development; multicellular organism growth; negative regulation of keratinocyte differentiation; embryonic cranial skeleton morphogenesis; positive regulation of telomerase activity; regulation of transcription from RNA polymerase II promoter; cell proliferation; regulation of transcription, DNA-dependent; regulation of gene expression; neural tube closure; embryonic organ development; positive regulation of transcription from RNA polymerase II promoter; embryonic digit morphogenesis; brain development; cell adhesion

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