Full Product Name
Sar1B Polyclonal Antibody
Product Gene Name
anti-Sar1B antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9Y6B6
Other Notes
Small volumes of anti-Sar1B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Sar1B. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001028675.1
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NCBI GenBank Nucleotide #
NM_001033503.2
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UniProt Primary Accession #
Q9Y6B6
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UniProt Secondary Accession #
Q567T4; D3DQA4[Other Products]
UniProt Related Accession #
Q9Y6B6[Other Products]
Molecular Weight
22,410 Da
NCBI Official Full Name
GTP-binding protein SAR1b
NCBI Official Synonym Full Names
secretion associated Ras related GTPase 1B
NCBI Official Symbol
SAR1B [Similar Products]
NCBI Official Synonym Symbols
ANDD; CMRD; GTBPB; SARA2
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NCBI Protein Information
GTP-binding protein SAR1b
UniProt Protein Name
GTP-binding protein SAR1b
UniProt Synonym Protein Names
GTP-binding protein B; GTBPB
Protein Family
GTP-binding protein
UniProt Gene Name
SAR1B [Similar Products]
UniProt Synonym Gene Names
SARA2; SARB; GTBPB [Similar Products]
NCBI Summary for Sar1B
The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]
UniProt Comments for Sar1B
Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex.
Research Articles on Sar1B
1. Report compensatory Sar1a elevation after Sar1b gene deletion in Caco-2/15 cells prevents chylomicron collapse.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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