Full Product Name
B3GALTL Antibody
Product Synonym Names
B3Glc-T; B3GLT; B3GTL; beta 1, 3-galactosyltransferase-like; beta-1, 3-glucosyltransferase; beta-3-glycosyltransferase-like; beta3Glc-T; EC 2.4.1.-; Gal-T
Product Gene Name
anti-B3GALTL antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q6Y288
Specificity
B3GALTL antibody detects endogenous levels of total B3GALTL protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of human B3GALTL.
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-B3GALTL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-B3GALTL antibody
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
Applications Tested/Suitable for anti-B3GALTL antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-B3GALTL antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:40000
Testing Data of anti-B3GALTL antibody
Peptide-+
Immunohistochemistry (IHC) of anti-B3GALTL antibody
Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using B3GALTL antibody. Western blot analysis of extracts from HepG2 cells, Jurkat cells, MCF-7 cells and HUVEC cells, using B3GALTL antibody.
NCBI/Uniprot data below describe general gene information for B3GALTL. It may not necessarily be applicable to this product.
NCBI Accession #
NP_919299.3
[Other Products]
NCBI GenBank Nucleotide #
NM_194318.3
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UniProt Primary Accession #
Q6Y288
[Other Products]
UniProt Secondary Accession #
Q5W0H2; Q6NUI3; A8K5F8[Other Products]
UniProt Related Accession #
Q6Y288[Other Products]
Molecular Weight
56,564 Da
NCBI Official Full Name
beta-1,3-glucosyltransferase
NCBI Official Synonym Full Names
beta 3-glucosyltransferase
NCBI Official Symbol
B3GLCT [Similar Products]
NCBI Official Synonym Symbols
B3GTL; Gal-T; B3GALTL; B3Glc-T; beta3Glc-T
[Similar Products]
NCBI Protein Information
beta-1,3-glucosyltransferase
UniProt Protein Name
Beta-1,3-glucosyltransferase
UniProt Synonym Protein Names
Beta 3-glucosyltransferase
UniProt Gene Name
B3GLCT [Similar Products]
UniProt Synonym Gene Names
Beta3Glc-T [Similar Products]
NCBI Summary for B3GALTL
The protein encoded by this gene is a beta-1,3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats (TSRs) of several proteins. The encoded protein is a type II membrane protein. Defects in this gene are a cause of Peters-plus syndrome (PPS).[provided by RefSeq, Mar 2009]
UniProt Comments for B3GALTL
O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.
Product References and Citations for anti-B3GALTL antibody
Heinonen T.Y.K., Biochem. Biophys. Res. Commun. 309:166-174(2003). Sato T., Glyco
biology 16:1194-1206(2006). Dunham A., Nature 428:522-528(2004).
Research Articles on B3GALTL
1. Studies indicate that Peters Plus syndrome is caused by mutations in beta 3-glucosyltransferase (B3GALTL).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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