Full Product Name
ADH1B, ID (Alcohol Dehydrogenase 1B, Alcohol Dehydrogenase Subunit beta, ADH2)
Product Synonym Names
Anti -ADH1B, ID (Alcohol Dehydrogenase 1B, Alcohol Dehydrogenase Subunit beta, ADH2)
Product Gene Name
anti-ADH1B antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 4; NC_000004.11 (100227527..100242572, complement). Location: 4q23
3D Structure
ModBase 3D Structure for P00325
Specificity
Recognizes human ADH1B.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Immunogen
Synthetic peptide selected from the Center region of human ADH1B (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-ADH1B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ADH1B antibody
The protein is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism.
Product Categories/Family for anti-ADH1B antibody
Antibodies; Abs to Enzymes, Dehydrogenase
Applications Tested/Suitable for anti-ADH1B antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-ADH1B antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100
NCBI/Uniprot data below describe general gene information for ADH1B. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000659.2
[Other Products]
NCBI GenBank Nucleotide #
NM_000668.4
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UniProt Primary Accession #
P00325
[Other Products]
UniProt Secondary Accession #
Q13711; Q4ZGI9; Q96KI7[Other Products]
UniProt Related Accession #
P00325[Other Products]
Molecular Weight
39,855 Da[Similar Products]
NCBI Official Full Name
alcohol dehydrogenase 1B
NCBI Official Synonym Full Names
alcohol dehydrogenase 1B (class I), beta polypeptide
NCBI Official Symbol
ADH1B [Similar Products]
NCBI Official Synonym Symbols
ADH2; DKFZp686C06125
[Similar Products]
NCBI Protein Information
alcohol dehydrogenase 1B; ADH, beta subunit; OTTHUMP00000220192; aldehyde reductase; alcohol dehydrogenase subunit beta; alcohol dehydrogenase 2 (class I), beta polypeptide
UniProt Protein Name
Alcohol dehydrogenase 1B
UniProt Synonym Protein Names
Alcohol dehydrogenase subunit beta
UniProt Gene Name
ADH1B [Similar Products]
UniProt Synonym Gene Names
ADH2 [Similar Products]
UniProt Entry Name
ADH1B_HUMAN
NCBI Summary for ADH1B
The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. [provided by RefSeq]
UniProt Comments for ADH1B
ADH1B: Dimer of identical or non-identical chains of three types; alpha, beta and gamma. Belongs to the zinc-containing alcohol dehydrogenase family.
Protein type: Lipid Metabolism - fatty acid; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Oxidoreductase; EC 1.1.1.1; Cofactor and Vitamin Metabolism - retinol; Xenobiotic Metabolism - metabolism by cytochrome P450; Amino Acid Metabolism - tyrosine; Xenobiotic Metabolism - drug metabolism - cytochrome P450
Chromosomal Location of Human Ortholog: 4q23
Cellular Component: cytosol
Molecular Function: zinc ion binding; alcohol dehydrogenase activity, zinc-dependent
Biological Process: xenobiotic metabolic process; ethanol oxidation
Disease: Alcohol Dependence
Research Articles on ADH1B
1. ability of ADH isozymes to oxidize ethanol was in part regulated by product inhibition of ADH by acetaldehyde
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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