Acetyl Coenzyme A Acyltransferase 2 (ACAA2), Polyclonal Antibody

DSAEC; T1; Mitochondrial 3-Oxoacyl-Coenzyme A Thiolase; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Rabbit

200ug/ml (lot specific)

Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Small volumes of anti-ACAA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Western Blot (WB), Immunohistochemistry (IHC)

41,924 Da

acetyl-CoA acyltransferase 2

3-ketoacyl-CoA thiolase, mitochondrial

3-ketoacyl-CoA thiolase, mitochondrial

The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal. [provided by RefSeq, Jul 2008]

ACAA2: Abolishes BNIP3-mediated apoptosis and mitochondrial damage. Belongs to the thiolase family.

Protein type: Amino Acid Metabolism - valine, leucine and isoleucine degradation; EC 2.3.1.16; Lipid Metabolism - fatty acid; Lipid Metabolism - fatty acid elongation in mitochondria; Transferase

Chromosomal Location of Human Ortholog: 18q21.1

Cellular Component: extracellular exosome; mitochondrial inner membrane; mitochondrial matrix; mitochondrion

Molecular Function: acetyl-CoA C-acyltransferase activity; protein binding; RNA binding

Biological Process: cellular response to hypoxia; cholesterol biosynthetic process; fatty acid beta-oxidation; negative regulation of mitochondrial membrane permeability involved in apoptotic process; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

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