Product Name
ACAD-9, Polyclonal Antibody
Full Product Name
ACAD-9 Polyclonal Antibody
Product Gene Name
anti-ACAD-9 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9H845
Other Notes
Small volumes of anti-ACAD-9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ACAD-9. It may not necessarily be applicable to this product.
NCBI Accession #
NP_054768.2
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NCBI GenBank Nucleotide #
NM_014049.4
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UniProt Primary Accession #
Q9H845
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UniProt Secondary Accession #
Q8WXX3; D3DNB8[Other Products]
UniProt Related Accession #
Q9H845[Other Products]
Molecular Weight
68,760 Da
NCBI Official Full Name
acyl-CoA dehydrogenase family member 9, mitochondrial
NCBI Official Synonym Full Names
acyl-CoA dehydrogenase family member 9
NCBI Official Symbol
ACAD9 [Similar Products]
NCBI Official Synonym Symbols
NPD002
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NCBI Protein Information
acyl-CoA dehydrogenase family member 9, mitochondrial
UniProt Protein Name
Acyl-CoA dehydrogenase family member 9, mitochondrial
UniProt Gene Name
ACAD9 [Similar Products]
UniProt Synonym Gene Names
ACAD-9 [Similar Products]
NCBI Summary for ACAD-9
This gene encodes a member of the acyl-CoA dehydrogenase family. Members of this family of proteins localize to the mitochondria and catalyze the rate-limiting step in the beta-oxidation of fatty acyl-CoA. The encoded protein is specifically active toward palmitoyl-CoA and long-chain unsaturated substrates. Mutations in this gene cause acyl-CoA dehydrogenase family member type 9 deficiency. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2010]
UniProt Comments for ACAD-9
Required for mitochondrial complex I assembly (PubMed:20816094, PubMed:24158852). Has a dehydrogenase activity on palmitoyl-CoA (C16:0) and stearoyl-CoA (C18:0). It is three times more active on palmitoyl-CoA than on stearoyl-CoA. However, it does not play a primary role in long-chain fatty acid oxidation in vivo (PubMed:20816094, PubMed:24158852). Has little activity on octanoyl-CoA (C8:0), butyryl-CoA (C4:0) or isovaleryl-CoA (5:0).
Research Articles on ACAD-9
1. Study identified new mutations in ACAD9 responsible for a wide spectrum of heart diseases in the presence of elevated serum lactate levels.
Precautions
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Disclaimer
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