Full Product Name
ACAD9 Polyclonal Antibody
Product Synonym Names
NPD002
Product Gene Name
anti-ACAD9 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
MSGCGLFLRT TAAARACRGL VVSTANRRLL RTSPPVRAFA KELFLGKIKK KEVFPFPEVS QDELNEINQF LGPVEKFFTE EVDSRKIDQE GKIPDETLEK LKSLGLFGLQ VPEEYGGLGF SNTMYSRLGE IISMDGSITV TLAAHQAIGL KGIILAGTEE QKAKYLPKLA SGEHIAAFCL TEPASGSDAA SIRSRATLSE DKKHYILNGS KVWITNGGLA NIFTVFAKTE VVDSDGSVKD KITAFIVERD FGGVT
3D Structure
ModBase 3D Structure for Q9H845
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Immunogen
Recombinant protein of human ACAD9
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location
Mitochondrion
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Other Notes
Small volumes of anti-ACAD9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ACAD9 antibody
This gene encodes a member of the acyl-CoA dehydrogenase family. Members of this family of proteins localize to the mitochondria and catalyze the rate-limiting step in the beta-oxidation of fatty acyl-CoA. The encoded protein is specifically active toward palmitoyl-CoA and long-chain unsaturated substrates. Mutations in this gene cause acyl-CoA dehydrogenase family member type 9 deficiency. Alternate splicing results in multiple transcript variants.
Product Categories/Family for anti-ACAD9 antibody
Polyclonal Antibodies
Applications Tested/Suitable for anti-ACAD9 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ACAD9 antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
NCBI/Uniprot data below describe general gene information for ACAD9. It may not necessarily be applicable to this product.
NCBI Accession #
NP_054768.2
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NCBI GenBank Nucleotide #
NM_014049.4
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UniProt Primary Accession #
Q9H845
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UniProt Secondary Accession #
Q8WXX3; D3DNB8[Other Products]
UniProt Related Accession #
Q9H845[Other Products]
NCBI Official Full Name
acyl-CoA dehydrogenase family member 9, mitochondrial
NCBI Official Synonym Full Names
acyl-CoA dehydrogenase family member 9
NCBI Official Symbol
ACAD9 [Similar Products]
NCBI Official Synonym Symbols
NPD002
[Similar Products]
NCBI Protein Information
acyl-CoA dehydrogenase family member 9, mitochondrial
UniProt Protein Name
Acyl-CoA dehydrogenase family member 9, mitochondrial
Protein Family
Acyl-CoA dehydrogenase family
UniProt Gene Name
ACAD9 [Similar Products]
UniProt Synonym Gene Names
ACAD-9 [Similar Products]
NCBI Summary for ACAD9
This gene encodes a member of the acyl-CoA dehydrogenase family. Members of this family of proteins localize to the mitochondria and catalyze the rate-limiting step in the beta-oxidation of fatty acyl-CoA. The encoded protein is specifically active toward palmitoyl-CoA and long-chain unsaturated substrates. Mutations in this gene cause acyl-CoA dehydrogenase family member type 9 deficiency. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2010]
UniProt Comments for ACAD9
Required for mitochondrial complex I assembly (PubMed:20816094, PubMed:24158852). Has a dehydrogenase activity on palmitoyl-CoA (C16:0) and stearoyl-CoA (C18:0). It is three times more active on palmitoyl-CoA than on stearoyl-CoA. However, it does not play a primary role in long-chain fatty acid oxidation in vivo (PubMed:20816094, PubMed:24158852). Has little activity on octanoyl-CoA (C8:0), butyryl-CoA (C4:0) or isovaleryl-CoA (5:0).
Research Articles on ACAD9
1. Study identified new mutations in ACAD9 responsible for a wide spectrum of heart diseases in the presence of elevated serum lactate levels.
Precautions
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Disclaimer
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