ACAD9, Polyclonal Antibody

NPD002

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Rabbit

The antibody detects endogenous levels of total ACAD9 protein.

Antigen affinity purification.

Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

0.5 mg/ml (lot specific)

Store at -20 degree C

Small volumes of anti-ACAD9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

This gene encodes a member of the acyl-CoA dehydrogenase family. Members of this family of proteins localize to the mitochondria and catalyze the rate-limiting step in the beta-oxidation of fatty acyl-CoA. The encoded protein is specifically active toward palmitoyl-CoA and long-chain unsaturated substrates. Mutations in this gene cause acyl-CoA dehydrogenase family member type 9 deficiency. Alternate splicing results in multiple transcript variants.

Total protein Ab

Immunohistochemistry (IHC)

Immunohistochemistry: 1:25-1:100

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using at dilution 1/10.

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/10.

68,760 Da

acyl-CoA dehydrogenase family, member 9

acyl-CoA dehydrogenase family member 9, mitochondrial

Acyl-CoA dehydrogenase family member 9, mitochondrial

ACAD-9  [Similar Products]

ACAD9_HUMAN

This gene encodes a member of the acyl-CoA dehydrogenase family. Members of this family of proteins localize to the mitochondria and catalyze the rate-limiting step in the beta-oxidation of fatty acyl-CoA. The encoded protein is specifically active toward palmitoyl-CoA and long-chain unsaturated substrates. Mutations in this gene cause acyl-CoA dehydrogenase family member type 9 deficiency. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2010]

ACAD9: Has a dehydrogenase activity on palmitoyl-CoA (C16:0) and stearoyl-CoA (C18:0). It is three times more active on palmitoyl-CoA then on stearoyl-CoA. Has little activity on octanoyl-CoA (C8:0), butyryl-CoA (C4:0) or isovaleryl-CoA (5:0). Belongs to the acyl-CoA dehydrogenase family.

Protein type: Mitochondrial; EC 1.3.99.-; Oxidoreductase

Chromosomal Location of Human Ortholog: 3q21.3

Cellular Component: mitochondrion; dendrite; nucleus

Molecular Function: acyl-CoA dehydrogenase activity; protein binding; FAD binding

Biological Process: mitochondrial respiratory chain complex I assembly

Disease: Acyl-coa Dehydrogenase Family, Member 9, Deficiency Of

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