Product Name
Lamin B Receptor (LBR), Polyclonal Antibody
Full Product Name
Anti-Lamin B Receptor Rabbit pAb
Product Gene Name
anti-LBR antibody
[Similar Products]
Product Synonym Gene Name
PHA; LMN2R; TDRD18; DHCR14B[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q14739
Species Reactivity
Human, Rat
Specificity
Lamin B Receptor Antibodydetects endogenous levels of total Lamin B Receptor
Purity/Purification
Affinity Chromatography
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
A synthesized peptide derived from human Lamin B Receptor
Subcellular Location
Membrane
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.
Other Notes
Small volumes of anti-LBR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-LBR antibody
The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Applications Tested/Suitable for anti-LBR antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)
Application Notes for anti-LBR antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:100-1:500
IP: 1:30
Western Blot (WB) of anti-LBR antibody
Western blot analysis of Lamin B Receptor expression in Jurkat cell lysate.
NCBI/Uniprot data below describe general gene information for LBR. It may not necessarily be applicable to this product.
NCBI Accession #
NP_002287.2
[Other Products]
NCBI GenBank Nucleotide #
NM_002296.3
[Other Products]
UniProt Primary Accession #
Q14739
[Other Products]
UniProt Secondary Accession #
Q14740; Q53GU7; Q59FE6; B2R5P3[Other Products]
UniProt Related Accession #
Q14739[Other Products]
NCBI Official Full Name
lamin-B receptor
NCBI Official Synonym Full Names
lamin B receptor
NCBI Official Symbol
LBR [Similar Products]
NCBI Official Synonym Symbols
PHA; LMN2R; TDRD18; DHCR14B
[Similar Products]
NCBI Protein Information
lamin-B receptor
UniProt Protein Name
Lamin-B receptor
UniProt Synonym Protein Names
Integral nuclear envelope inner membrane protein; LMN2R
Protein Family
Lamin-B receptor
UniProt Gene Name
LBR [Similar Products]
NCBI Summary for LBR
The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for LBR
Anchors the lamina and the heterochromatin to the inner nuclear membrane.
Research Articles on LBR
1. The authors demonstrate that human LBR is essential for cholesterol synthesis.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
