Product Name
BPIFB1, Polyclonal Antibody
Full Product Name
BPIFB1 (C20orf114, BPI Fold-containing Family B Member 1, Long Palate, Lung and Nasal Epithelium Carcinoma-associated Protein 1, Von Ebner Minor Salivary Gland Protein, VEMSGP, LPLUNC1, UNQ706/PRO1357, MGC14597)
Product Synonym Names
Anti -BPIFB1 (C20orf114, BPI Fold-containing Family B Member 1, Long Palate, Lung and Nasal Epithelium Carcinoma-associated Protein 1, Von Ebner Minor Salivary Gland Protein, VEMSGP, LPLUNC1, UNQ706/PRO1357, MGC14597)
Product Gene Name
anti-BPIFB1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
MAGPWTFTLL CGLLAATLIQ ATLSPTAVLI LGPKVIKEKL TQELKDHNAT SILQQLPLLS AMREKPAGGI PVLGSLVNTV LKHVIWLKVI TANILQLQVK PSANDQELLV KIPLDMVAGF NTPLVKTIVE FHMTTEAQAT IRMDTSASGP TRLVLSDCAT SHGSLRIQLL HKLSFLVNAL AKQVMNLLVP SLPNLVKNQL CPVIEASFNG MYADLLQLVK VPISLSIDRL EFDLLYPAIK GDTIQLYLGA KLLDSQGKVT KWFNNSAASL TMPTLDNIPF SLIVSQDVVK AAVAAVLSPE EFMVLLDSVL PESAHRLKSS IGLINEKAAD KLGSTQIVKI LTQDTPEFFI DQGHAKVAQL IVLEVFPSSE ALRPLFTLGI EASSEAQFYT KGDQLILNLN NISSDRIQLM NSGIGWFQPD VLKNIITEII HSILLPNQNG KLRSGVPVSL VKALGFEAAE SSLSKDALVL TPASLWKPTS PVSQ
Chromosome Location
Chromosome: 20; NC_000020.10 (31870941..31897684). Location: 20q11.21
3D Structure
ModBase 3D Structure for Q8TDL5
Specificity
Recognizes human C20orf114.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Immunogen
Full length human C20orf114, aa1-484 (AAH08429.1).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-BPIFB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-BPIFB1 antibody
May play a role in innate immunity in mouth, nose and lungs.
Product Categories/Family for anti-BPIFB1 antibody
Antibodies; Abs to Proteins
Applications Tested/Suitable for anti-BPIFB1 antibody
Western Blot (WB)
Application Notes for anti-BPIFB1 antibody
Suitable for use in Western Blot.
NCBI/Uniprot data below describe general gene information for BPIFB1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_149974.2
[Other Products]
NCBI GenBank Nucleotide #
NM_033197.2
[Other Products]
UniProt Primary Accession #
Q8TDL5
[Other Products]
UniProt Secondary Accession #
Q5QP43; Q6UWY1; Q6ZRU7; Q96HK6; Q9BQP8; Q9BWZ6; Q9H4V6; A8K2H8[Other Products]
UniProt Related Accession #
Q8TDL5[Other Products]
Molecular Weight
52,442 Da[Similar Products]
NCBI Official Full Name
BPI fold-containing family B member 1
NCBI Official Synonym Full Names
BPI fold containing family B, member 1
NCBI Official Symbol
BPIFB1 [Similar Products]
NCBI Official Synonym Symbols
LPLUNC1; C20orf114
[Similar Products]
NCBI Protein Information
BPI fold-containing family B member 1; VEMSGP; von Ebner minor salivary gland protein; long palate, lung and nasal epithelium carcinoma associated 1; long palate, lung and nasal epithelium carcinoma-associated protein 1
UniProt Protein Name
BPI fold-containing family B member 1
UniProt Synonym Protein Names
Long palate, lung and nasal epithelium carcinoma-associated protein 1; Von Ebner minor salivary gland protein
Protein Family
BPI fold-containing family
UniProt Gene Name
BPIFB1 [Similar Products]
UniProt Synonym Gene Names
C20orf114; LPLUNC1; VEMSGP [Similar Products]
UniProt Entry Name
BPIB1_HUMAN
NCBI Summary for BPIFB1
The protein encoded by this gene may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. The encoded protein is secreted and is a member of the BPI/LBP/PLUNC protein superfamily. This gene is found with other members of the superfamily in a cluster on chromosome 20. [provided by RefSeq, Jul 2008]
UniProt Comments for BPIFB1
LPLUNC1: May play a role in innate immunity in mouth, nose and lungs. Belongs to the BPI/LBP/Plunc superfamily. Plunc family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 20q11.21
Cellular Component: extracellular space; extracellular region
Molecular Function: lipid binding
Biological Process: innate immune response in mucosa; negative regulation of toll-like receptor 4 signaling pathway
Research Articles on BPIFB1
1. It was shown that there was a significant increase in LPLUNC1 in the airways of patients with cystic fibrosis, but it is unclear if this increase influences the development of lung disease.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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