Product Name
IL31, Polyclonal Antibody
Popular Item
Full Product Name
IL31 Polyclonal Antibody
Product Synonym Names
IL-31
Product Gene Name
anti-IL31 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS2526798 Technical Datasheet
Technical Datasheet PDF
Purity/Purification
Antigen affinity purification
Concentration
1.3mg/mL (lot specific)
Immunogen
Synthetic peptide of human IL31
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Note
Centrifuge before opening to ensure complete recovery of vial contents.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-IL31 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-IL31 antibody
IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma
Applications Tested/Suitable for anti-IL31 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-IL31 antibody
IHC: 1:50-1:200
Immunohistochemistry (IHC) of anti-IL31 antibody
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using IL31 Polyclonal Antibody at dilution 1:20
Immunohistochemistry (IHC) of anti-IL31 antibody
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using IL31 Polyclonal Antibody at dilution 1:20
NCBI/Uniprot data below describe general gene information for IL31. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001014358.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001014336.1
[Other Products]
UniProt Secondary Accession #
A2RUQ1[Other Products]
UniProt Related Accession #
Q6EBC2[Other Products]
Molecular Weight
18,205 Da
NCBI Official Full Name
interleukin-31
NCBI Official Synonym Full Names
interleukin 31
NCBI Official Symbol
IL31 [Similar Products]
NCBI Official Synonym Symbols
IL-31
[Similar Products]
NCBI Protein Information
interleukin-31
UniProt Protein Name
Interleukin-31
Protein Family
Interleukin
UniProt Gene Name
IL31 [Similar Products]
UniProt Synonym Gene Names
IL-31 [Similar Products]
UniProt Entry Name
IL31_HUMAN
NCBI Summary for IL31
IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008]
UniProt Comments for IL31
IL31: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity.
Protein type: Secreted; Cytokine; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 12q24.31
Cellular Component: extracellular space
Molecular Function: cytokine activity
Biological Process: immune system process
Research Articles on IL31
1. IL-31 may play an important role in the pathophysiology of uremic pruritus.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
