Product Name
Aconitase (ACO2), Enzyme
Full Product Name
Aconitase (Pig Heart)
Product Synonym Names
Aconitase (Pig heart); Aconitase
Product Gene Name
ACO2 enzyme
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 5; NC_007303.4 (119518293..119567339). Location: 5q35
3D Structure
ModBase 3D Structure for P20004
Form/Format
50% Glycerol Solution
Specifications
Citrate (isocitrate) hydro-lyase (EC 4.2.1.3) from pig heart
Specific Activity
> 5 U/mg protein (at 25 degree C and pH 7.4)
State
Highly purified enzyme in solution
One mL of solution contains the following
Protein 1 ~ 30 mg
Glycerol 50 %
pH 7.0 +/- 0.5
Preparation
50% Glycerol Solution
Preparation and Storage
At -20 degree C.
Other Notes
Small volumes of ACO2 enzyme vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for ACO2 enzyme
Enzymes
NCBI/Uniprot data below describe general gene information for ACO2. It may not necessarily be applicable to this product.
UniProt Primary Accession #
P20004
[Other Products]
UniProt Secondary Accession #
Q3SZZ1[Other Products]
UniProt Related Accession #
P20004; Q1P9Q3[Other Products]
Molecular Weight
85,359 Da[Similar Products]
NCBI Official Full Name
aconitase
NCBI Official Symbol
ACO2 [Similar Products]
NCBI Protein Information
aconitate hydratase, mitochondrial; citrate hydro-lyase
UniProt Protein Name
Aconitate hydratase, mitochondrial
UniProt Synonym Protein Names
Citrate hydro-lyase
Protein Family
Aconitate hydratase
UniProt Gene Name
ACO2 [Similar Products]
UniProt Entry Name
ACON_BOVIN
UniProt Comments for ACO2
Function: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
Catalytic activity: Citrate = isocitrate.
Cofactor: Binds 1 4Fe-4S cluster per subunit. Binding of a 3Fe-4S cluster leads to an inactive enzyme.
Pathway: Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.
Subunit structure: Monomer.
Subcellular location: Mitochondrion.
Sequence similarities: Belongs to the aconitase/IPM isomerase family.
Precautions
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Disclaimer
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