Full Product Name
Anti-GDF1 Antibody
Product Gene Name
anti-GDF1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Immunogen
A synthetic peptide of human GDF1
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-GDF1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GDF1 antibody
This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily.
Applications Tested/Suitable for anti-GDF1 antibody
Western Blot (WB)
Application Notes for anti-GDF1 antibody
WB: 1:200-1:1000
NCBI/Uniprot data below describe general gene information for GDF1. It may not necessarily be applicable to this product.
NCBI Accession #
AAH22450.1
[Other Products]
UniProt Secondary Accession #
O43344[Other Products]
UniProt Related Accession #
P27539[Other Products]
Molecular Weight
39,475 Da
NCBI Official Full Name
GDF1 protein
NCBI Official Synonym Full Names
growth differentiation factor 1
NCBI Official Symbol
GDF1 [Similar Products]
NCBI Official Synonym Symbols
RAI; DORV; CHTD6; DTGA3
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NCBI Protein Information
embryonic growth/differentiation factor 1
UniProt Protein Name
Embryonic growth/differentiation factor 1
Protein Family
Embryonic growth/differentiation factor
UniProt Gene Name
GDF1 [Similar Products]
UniProt Synonym Gene Names
GDF-1 [Similar Products]
NCBI Summary for GDF1
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. The encoded protein is translated from a bicistronic mRNA that also encodes ceramide synthase 1. Mutations in this gene are associated with several congenital cardiovascular malformations. [provided by RefSeq, Jul 2016]
UniProt Comments for GDF1
May mediate cell differentiation events during embryonic development.
Research Articles on GDF1
1. Rare inherited and de novo variants in 2,871 congenital heart disease probands identified GDF1, MYH6, and FLT4 as causative genes.
Precautions
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Disclaimer
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