Product Name
NPBWR1, Blocking Peptide
Full Product Name
NPBWR1 Antibody (C-term) Blocking Peptide
Product Synonym Names
Neuropeptides B/W receptor type 1; G-protein coupled receptor 7; NPBWR1; GPR7
Product Gene Name
NPBWR1 blocking peptide
[Similar Products]
Product Synonym Gene Name
GPR7[Similar Products]
Antibody/Peptide Pairs
NPBWR1 peptide (MBS9223374) is used for blocking the activity of NPBWR1 antibody (MBS9204944)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P48145
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Cell membrane; Multi-pass membrane protein.
Tissue Location
Found in cerebellum and frontal cortex. Detected at high levels in hippocampus, amygdala and trachea; at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high levels in lung carcinoma.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of NPBWR1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
NPBWR1 blocking peptide
Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.
NCBI/Uniprot data below describe general gene information for NPBWR1. It may not necessarily be applicable to this product.
NCBI Accession #
P48145.2
[Other Products]
UniProt Primary Accession #
P48145
[Other Products]
UniProt Secondary Accession #
Q6NTC7[Other Products]
UniProt Related Accession #
P48145[Other Products]
Molecular Weight
36,103 Da
NCBI Official Full Name
Neuropeptides B/W receptor type 1
NCBI Official Synonym Full Names
neuropeptides B/W receptor 1
NCBI Official Symbol
NPBWR1 [Similar Products]
NCBI Official Synonym Symbols
GPR7
[Similar Products]
NCBI Protein Information
neuropeptides B/W receptor type 1
UniProt Protein Name
Neuropeptides B/W receptor type 1
UniProt Synonym Protein Names
G-protein coupled receptor 7
Protein Family
Neuropeptides B/W receptor
UniProt Gene Name
NPBWR1 [Similar Products]
UniProt Synonym Gene Names
GPR7 [Similar Products]
UniProt Entry Name
NPBW1_HUMAN
UniProt Comments for NPBWR1
NPBWR1: Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 8p22-q21.13
Cellular Component: integral to membrane; integral to plasma membrane; neuron projection; plasma membrane
Molecular Function: neuropeptide binding; opioid receptor activity; protein binding
Biological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; neuropeptide signaling pathway; synaptic transmission
Research Articles on NPBWR1
1. screening of GPR7 gene mutations among lean and obese subjects revealed a Tyr135Phe allelic variant that is fairly common in the study population. This variant is unlikely to cause a functional derangement of the receptor
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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