NPBWR1 / GPR7, Polyclonal Antibody

Anti-NPBWR1 / GPR7 Antibody (Cytoplasmic Domain) IHC-plus; NPBWR1; G protein-coupled receptor 7; GPR7; Neuropeptide B/W receptor 1; Neuropeptides B/W receptor 1; G-protein coupled receptor 7; Human NPBWR1; GPR7

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Rabbit

Human NPBWR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Immunoaffinity Purified

PBS, 0.1% sodium azide.

1 mg/ml (lot specific)

Long term: -70 degree C; Short term: +4 degree C

Small volumes of anti-NPBWR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

GPR7 is a Neuropeptide Receptor GPCR. GPR7 is implicated in the regulation of feeding, neuroendorine system, memory, and learning.

Subfamily:-Neuropeptide">Family: GPCR
Subfamily: Neuropeptide

Immunohistochemistry (IHC - Paraffin)

IHC-P (11 - 22 ug/ml)

Anti-NPBWR1 / GPR7 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-NPBWR1 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-NPBWR1 / GPR7 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

36,103 Da

neuropeptides B/W receptor 1

neuropeptides B/W receptor type 1; neuropeptide B/W receptor 1; G protein-coupled receptor 7; G-protein coupled receptor 7; opioid-somatostatin-like receptor 7

Neuropeptides B/W receptor type 1

GPR7  [Similar Products]

NPBW1_HUMAN

NPBWR1: Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCR

Chromosomal Location of Human Ortholog: 8p22-q21.13

Cellular Component: neuron projection; integral to plasma membrane; plasma membrane; integral to membrane

Molecular Function: neuropeptide binding; protein binding; neuropeptide receptor activity; opioid receptor activity

Biological Process: synaptic transmission; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; neuropeptide signaling pathway; regulation of metabolic process

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