Orexin receptor type 2, ELISA Kit

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C.

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Small volumes of HCRTR2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS2604632 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Orexin receptor type 2 (HCRTR2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HCRTR2. The ELISA analytical biochemical technique of the MBS2604632 kit is based on HCRTR2 antibody-HCRTR2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HCRTR2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HCRTR2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

50,694 Da

hypocretin receptor 2

orexin receptor type 2

Orexin receptor type 2

Ox-2-R; Ox2-R; Ox2R  [Similar Products]

OX2R_HUMAN

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A. [provided by RefSeq, Jan 2009]

HCRTR2: Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1

Chromosomal Location of Human Ortholog: 6p12

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: neuropeptide receptor activity; orexin receptor activity; peptide binding; peptide hormone binding

Biological Process: cellular response to hormone stimulus; circadian sleep/wake cycle process; feeding behavior; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); neuropeptide signaling pathway; regulation of circadian sleep/wake cycle, sleep; synaptic transmission

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