ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhib

Bovine Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (ARFGEF1) ELISA kit; ARFGEP1; BIG1; D730028O18Rik; DKFZP434L057; P200; brefeldin A-inhibited guanine nucleotide-exchange protein 1; ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of ARFGEF1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9321052 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) (ARFGEF1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ARFGEF1. The ELISA analytical biochemical technique of the MBS9321052 kit is based on ARFGEF1 antibody-ARFGEF1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ARFGEF1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ARFGEF1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

208,712 Da

brefeldin A-inhibited guanine nucleotide-exchange protein 1; p200 ARF-GEP1; brefeldin A-inhibited GEP 1; p200 ARF guanine nucleotide exchange factor; ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)

Brefeldin A-inhibited guanine nucleotide-exchange protein 1

ARFGEP1; BIG1; Brefeldin A-inhibited GEP 1  [Similar Products]

BIG1_BOVIN

Function: Promotes guanine-nucleotide exchange on ARF1 and ARF3. Promotes the activation of ARF1/ARF3 through replacement of GDP with GTP. Involved in vesicular trafficking. Required for the maintenance of Golgi structure; the function may be independent of its GEF activity. Required for the maturaion of integrin beta-1 in the Golgi. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. Proposed to act as A kinase-anchoring protein (AKAP) and may mediate crosstalk between Arf and PKA pathways. Inhibits GAP activity of MYO9B probably through competetive RhoA binding. The function in the nucleus remains to be determined

Enzyme regulation: Inhibited by brefeldin A.

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