Motor neuron and pancreas homeobox protein 1, ELISA Kit

Motor neuron and pancreas homeobox protein 1; Homeobox protein HB9; MNX1; HLXB9

For Research Use Only. Not for use in diagnostic procedures.

Store at 4 degree C

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Small volumes of MNX1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9427240 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Motor neuron and pancreas homeobox protein 1 (MNX1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MNX1. The ELISA analytical biochemical technique of the MBS9427240 kit is based on MNX1 antibody-MNX1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MNX1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MNX1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

20,553 Da

motor neuron and pancreas homeobox 1

motor neuron and pancreas homeobox protein 1

Motor neuron and pancreas homeobox protein 1

HLXB9  [Similar Products]

This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

MNX1: Putative transcription factor involved in pancreas development and function. Defects in MNX1 are a cause of Currarino syndrome (CURRAS). The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. The syndrome occurs in the majority of patients as an autosomal dominant trait.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 7q36.3

Cellular Component: cytosol; nucleolus; nucleus

Molecular Function: transcription factor activity

Biological Process: anatomical structure morphogenesis; endocrine pancreas development; humoral immune response; neurite morphogenesis; regulation of transcription from RNA polymerase II promoter; spinal cord motor neuron cell fate specification

Disease: Currarino Syndrome

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