Product Name
leptin receptor (LEPR), ELISA Kit
Full Product Name
Mouse Leptin receptor, LR/Ob-R ELISA Kit
Product Synonym Names
Mouse Leptin receptor; LR/Ob-R ELISA KIT; CD295; OBR; OB receptor; OTTHUMP00000010694; leptin receptor
Product Gene Name
LEPR elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
MBS700706 Testing Data
Testing Data PDF
3D Structure
ModBase 3D Structure for P48356
Specificity
This assay has high sensitivity and excellent specificity for detection of Mouse LEPR. No significant cross-reactivity or interference between Mouse LEPR and analogues was observed.
Samples
Serum, plasma and tissue homogenates
Detection Range
15.62pg/ml-1000 pg/ml
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
Detection Wavelength
450 nm
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of LEPR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for LEPR purchase
MBS700706 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the leptin receptor (LEPR) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LEPR. The ELISA analytical biochemical technique of the MBS700706 kit is based on LEPR antibody-LEPR antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LEPR antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LEPR. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Typical Testing Data/Standard Curve (for reference only) of LEPR elisa kit
NCBI/Uniprot data below describe general gene information for LEPR. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001116371.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001122899.1
[Other Products]
UniProt Primary Accession #
P48356
[Other Products]
UniProt Secondary Accession #
O35686; O54986; Q61215; Q64309; Q9QWG3; Q9QWV5[Other Products]
UniProt Related Accession #
P48356[Other Products]
Molecular Weight
130,789 Da
NCBI Official Full Name
leptin receptor isoform 3
NCBI Official Synonym Full Names
leptin receptor
NCBI Official Symbol
Lepr [Similar Products]
NCBI Official Synonym Symbols
db; Obr; obl; Leprb; Modb1; LEPROT; OB-RGRP; diabetes; obese-like
[Similar Products]
NCBI Protein Information
leptin receptor; B219; LEP-R; OB receptor; leptin receptor gene-related protein
UniProt Protein Name
Leptin receptor
UniProt Synonym Protein Names
B219; OB receptor; OB-R; CD_antigen: CD295
Protein Family
Leptin receptor
UniProt Gene Name
Lepr [Similar Products]
UniProt Synonym Gene Names
Db; Obr; LEP-R; OB-R [Similar Products]
UniProt Entry Name
LEPR_MOUSE
UniProt Comments for LEPR
Function: Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway.
Research Articles on LEPR
1. results demonstrate that leptin receptor is dramatically induced in the granulosa cells of ovulating follicles and this induction of Lepr expression requires the transcription factor CCAAT/enhancer-binding protein beta
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
