Product Name
Ihh (Q80XI9), Blocking Peptide
Product Gene Name
Q80XI9 blocking peptide
[Similar Products]
Antibody/Peptide Pairs
Ihh peptide (MBS9224735) is used for blocking the activity of Ihh antibody (MBS9213049)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q80XI9
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the N-term region of human Ihh. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of Q80XI9 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Q80XI9 blocking peptide
Intercellular signal essential for a variety of patterning events during development.
NCBI/Uniprot data below describe general gene information for Q80XI9. It may not necessarily be applicable to this product.
NCBI Accession #
Q80XI9
[Other Products]
UniProt Primary Accession #
Q80XI9
[Other Products]
UniProt Related Accession #
P97812[Other Products]
Molecular Weight
49,445 Da
NCBI Official Full Name
Indian hedgehog (Adult male intestinal mucosa cDNA, RIKEN full-length enriched library, clone:G630019N11 product:Indian hedgehog, full insert sequence)
NCBI Official Synonym Full Names
Indian hedgehog
NCBI Official Symbol
Ihh [Similar Products]
NCBI Official Synonym Symbols
HHG-2
[Similar Products]
NCBI Protein Information
indian hedgehog protein
UniProt Protein Name
Hedgehog protein
UniProt Gene Name
Ihh [Similar Products]
UniProt Entry Name
Q80XI9_MOUSE
UniProt Comments for Q80XI9
IHH: Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP). Expressed in embryonic lung, and in ***** kidney and liver. Belongs to the hedgehog family.
Cellular Component: plasma membrane; proteinaceous extracellular matrix
Molecular Function: calcium ion binding; patched binding; protein binding
Biological Process: bone resorption; camera-type eye development; cartilage development; cell differentiation; cell fate specification; cell maturation; embryonic camera-type eye morphogenesis; embryonic development; embryonic digestive tract morphogenesis; embryonic digit morphogenesis; embryonic pattern specification; heart looping; in utero embryonic development; morphogenesis of a branching structure; multicellular organism growth; negative regulation of alpha-beta T cell differentiation; negative regulation of apoptosis; negative regulation of cell differentiation; negative regulation of eye pigmentation; negative regulation of immature T cell proliferation in the thymus; negative regulation of signal transduction; negative regulation of T cell differentiation in the thymus; neuron development; ossification; osteoblast differentiation; pancreas development; pattern specification process; patterning of blood vessels; positive regulation of alpha-beta T cell differentiation; positive regulation of cell proliferation; positive regulation of chondrocyte differentiation; positive regulation of collagen biosynthetic process; positive regulation of epithelial cell proliferation; positive regulation of mesenchymal cell proliferation; positive regulation of smoothened signaling pathway; positive regulation of T cell differentiation in the thymus; positive regulation of transcription from RNA polymerase II promoter; proteoglycan metabolic process; regulation of cell differentiation; regulation of growth; skeletal development; smooth muscle development; smoothened signaling pathway; vasculature development; vitelline membrane formation
Research Articles on Q80XI9
1. In organogenesis of the ovary, production of Dhh/Ihh in granulosa cells requires growth differentiation factor 9 from the oocyte.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
