Product Name
APOL4, Blocking Peptide
Full Product Name
APOL4 Antibody (Center E273) Blocking Peptide
Product Synonym Names
Apolipoprotein L4; Apolipoprotein L-IV; ApoL-IV; APOL4
Product Gene Name
APOL4 blocking peptide
[Similar Products]
Antibody/Peptide Pairs
APOL4 peptide (MBS9226327) is used for blocking the activity of APOL4 antibody (MBS9203715)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9BPW4
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the Center region of human APOL4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Secreted.
Tissue Location
Widely expressed; the highest levels are in spinal cord, placenta, adrenal gland; also detected in spleen, bone marrow, uterus, trachea, mammary gland and testis; levels are low in brain, heart and pancreas
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of APOL4 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
APOL4 blocking peptide
May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver (By similarity).
NCBI/Uniprot data below describe general gene information for APOL4. It may not necessarily be applicable to this product.
NCBI Accession #
Q9BPW4.3
[Other Products]
UniProt Primary Accession #
Q9BPW4
[Other Products]
UniProt Secondary Accession #
Q9BQ37; Q9BXQ8[Other Products]
UniProt Related Accession #
Q9BPW4[Other Products]
Molecular Weight
38,619 Da
NCBI Official Full Name
Apolipoprotein L4
NCBI Official Synonym Full Names
apolipoprotein L4
NCBI Official Symbol
APOL4 [Similar Products]
NCBI Official Synonym Symbols
APOLIV; APOL-IV
[Similar Products]
NCBI Protein Information
apolipoprotein L4
UniProt Protein Name
Apolipoprotein L4
UniProt Synonym Protein Names
Apolipoprotein L-IV; ApoL-IV
Protein Family
Apolipoprotein
UniProt Gene Name
APOL4 [Similar Products]
UniProt Synonym Gene Names
ApoL-IV [Similar Products]
UniProt Entry Name
APOL4_HUMAN
NCBI Summary for APOL4
The protein encoded by this gene is a member of the apolipoprotein L family and may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Two transcript variants encoding two different isoforms have been found for this gene. Only one of the isoforms appears to be a secreted protein. [provided by RefSeq, Jul 2008]
UniProt Comments for APOL4
APOL4: May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. Belongs to the apolipoprotein L family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Lipid-binding; Secreted
Chromosomal Location of Human Ortholog: 22q11.2-q13.2
Cellular Component: extracellular space; intracellular membrane-bound organelle
Disease: Schizophrenia
Research Articles on APOL4
1. An association of APOL1, 2 and 4 with schizophrenia was establised.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
