Product Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 (Plch1), Recombinant Protein
Full Product Name
Recombinant Mouse 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 (Plch1) , partial
Product Gene Name
Plch1 recombinant protein
[Similar Products]
Product Synonym Gene Name
Plch1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q4KWH5
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Plch1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Plch1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001171203.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001177732.1
[Other Products]
UniProt Primary Accession #
Q4KWH5
[Other Products]
UniProt Secondary Accession #
Q4KWH6; Q4KWH7; Q69ZS3; Q7TPQ1; Q8CFQ2[Other Products]
UniProt Related Accession #
Q4KWH5[Other Products]
Molecular Weight
55,818 Da
NCBI Official Full Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform 3
NCBI Official Synonym Full Names
phospholipase C, eta 1
NCBI Official Symbol
Plch1 [Similar Products]
NCBI Official Synonym Symbols
Plcl3; PLCeta1; BC042549; PLC-eta-1
[Similar Products]
NCBI Protein Information
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1
UniProt Protein Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1
UniProt Synonym Protein Names
Phosphoinositide phospholipase C-eta-1; Phospholipase C-eta-1; PLC-eta-1; Phospholipase C-like protein 3; PLC-L3
Protein Family
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
UniProt Gene Name
Plch1 [Similar Products]
UniProt Synonym Gene Names
Kiaa1069; Plcl3; PLC-eta-1; PLC-L3 [Similar Products]
UniProt Comments for Plch1
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by calcium-activated phosphatidylinositol-specific phospholipase C enzymes.
Research Articles on Plch1
1. Study concludes that perinuclear PLCepsilon, scaffolded to mAKAP in cardiac myocytes, responds to hypertrophic stimuli to generate diacylglycerol (DAG) from PI4P in the Golgi apparatus, in close proximity to the nuclear envelope, to regulate activation of nuclear PKD and hypertrophic signaling pathways.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
