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1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1, ELISA Kit

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产品名称: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1, ELISA Kit
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简单介绍

1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1, ELISA Kit


1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1, ELISA Kit  的详细介绍
Product Name

1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 (Plcb1), ELISA Kit

Full Product Name

Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 ELISA Kit

Product Synonym Names
1-phosphatidylinositol-4; 5-bisphosphate phosphodiesterase beta-1; PLC-154; Phosphoinositide phospholipase C-beta-1; Phospholipase C-I; PLC-I; Phospholipase C-beta-1; PLC-beta-1
Product Gene Name

Plcb1 elisa kit

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Request for Current Manual Insert
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3D Structure
ModBase 3D Structure for P10687
Species Reactivity
Rat
Assay Type
Sandwich
Detection Range
0.312-20 ng/mL
Sensitivity
0.162 ng/mL
Intra-Assay CV
<=4.7%
Inter-Assay CV
<=6.3%
Recovery
101%
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of Plcb1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for Plcb1 purchase
MBS2884194 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 (Plcb1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Plcb1. The ELISA analytical biochemical technique of the MBS2884194 kit is based on Plcb1 antibody-Plcb1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Plcb1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Plcb1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for Plcb1. It may not necessarily be applicable to this product.
NCBI GI #
117647200
NCBI GeneID
24654
NCBI Accession #
NP_001071109.1 [Other Products]
NCBI GenBank Nucleotide #
NM_001077641.1 [Other Products]
UniProt Primary Accession #
P10687 [Other Products]
UniProt Related Accession #
P10687[Other Products]
Molecular Weight
138,344 Da
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NCBI Official Full Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
NCBI Official Synonym Full Names
phospholipase C beta 1
NCBI Official Symbol
Plcb1  [Similar Products]
NCBI Official Synonym Symbols
PLC'1; Phosphb; PLCbeta1; RATPHOSPHB
  [Similar Products]
NCBI Protein Information
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
UniProt Protein Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
UniProt Synonym Protein Names
PLC-154; Phosphoinositide phospholipase C-beta-1; Phospholipase C-I; PLC-I; Phospholipase C-beta-1; PLC-beta-1
Protein Family
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
UniProt Gene Name
Plcb1  [Similar Products]
UniProt Synonym Gene Names
PLC-I; PLC-beta-1  [Similar Products]
UniProt Entry Name
PLCB1_RAT
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UniProt Comments for Plcb1
PLCB1: an enzyme that catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. Binds to calmodulin. Uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. Activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variant isoforms have been described.

Protein type: Carbohydrate Metabolism - inositol phosphate; EC 3.1.4.11; Phospholipase

Cellular Component: cytoplasm; cytosol; membrane; myelin sheath; nuclear chromatin; nuclear membrane; nuclear speck; nucleus

Molecular Function: calcium ion binding; calmodulin binding; enzyme binding; GTPase activator activity; lamin binding; phosphatidylinositol-4,5-bisphosphate binding; phosphoinositide phospholipase C activity; protein binding; protein homodimerization activity; signal transducer activity

Biological Process: acetylcholine receptor signaling, muscarinic pathway; brain development; cerebral cortex development; fat cell differentiation; G2/M transition of mitotic cell cycle; glutamate signaling pathway; insulin-like growth factor receptor signaling pathway; learning; lipid catabolic process; memory; negative regulation of transcription, DNA-dependent; phosphatidylinositol metabolic process; positive regulation of developmental growth; positive regulation of embryonic development; positive regulation of GTPase activity; positive regulation of interleukin-12 production; positive regulation of JNK cascade; positive regulation of myoblast differentiation; positive regulation of transcription, DNA-dependent; regulation of cell cycle; regulation of G-protein coupled receptor protein signaling pathway; response to organic nitrogen; response to peptide hormone stimulus
Research Articles on Plcb1
1. Results suggest that synergistic endocannabinoid mobilization in hippocampal CA1 neurons is greater in juveniles than in neonates, and that this may result from increases in the mGluR5-PLCbeta1 endocannabinoid pathway
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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