Product Name
Aminopeptidase O (AOPEP), Recombinant Protein
Full Product Name
Recombinant Human Aminopeptidase O (AOPEP) , partial
Product Gene Name
AOPEP recombinant protein
[Similar Products]
Product Synonym Gene Name
AOPEP[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8N6M6
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of AOPEP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for AOPEP. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001180258.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001193329.1
[Other Products]
UniProt Primary Accession #
Q8N6M6
[Other Products]
UniProt Secondary Accession #
Q5T9B1; Q5T9B3; Q5T9B4; Q8WUL6; Q96M23; Q96SS1[Other Products]
UniProt Related Accession #
Q8N6M6[Other Products]
Molecular Weight
77,937 Da
NCBI Official Full Name
aminopeptidase O isoform 1
NCBI Official Synonym Full Names
chromosome 9 open reading frame 3
NCBI Official Symbol
C9orf3 [Similar Products]
NCBI Official Synonym Symbols
APO; AP-O; AOPEP; ONPEP; C90RF3
[Similar Products]
NCBI Protein Information
aminopeptidase O
UniProt Protein Name
Aminopeptidase O
Protein Family
Aminopeptidase
UniProt Gene Name
AOPEP [Similar Products]
UniProt Synonym Gene Names
C9orf3; ONPEP; AP-O [Similar Products]
NCBI Summary for AOPEP
This gene encodes a member of the M1 zinc aminopeptidase family. The encoded protein is a zinc-dependent metallopeptidase that catalyzes the removal of an amino acid from the amino terminus of a protein or peptide. This protein may play a role in the generation of angiotensin IV. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010]
UniProt Comments for AOPEP
Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates. Able to cleave angiotensin III to generate angiotensin IV, a bioactive peptide of the renin-angiotensin pathway. Not able to cleave angiotensin I and angiotensin II. May play a role in the proteolytic processing of bioactive peptides in tissues such as testis and heart.
Research Articles on AOPEP
1. HPV-16 E6 was confirmed to regulate microRNA miR-23b indirectly through the DNA methylation of host gene C9orf3 and thus induce c-MET and inhibit apoptosis in cervical cancer cells.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
