Product Name
Ccbe1, Blocking Peptide
Full Product Name
Ccbe1 Peptide - C-terminal region
Product Gene Name
Ccbe1 blocking peptide
[Similar Products]
Product Synonym Gene Name
4933426F18Rik; 9430093N24Rik; KIAA1983; MGC118667; mKIAA1983[Similar Products]
Ccbe1 peptide (MBS3235808) is used for blocking the activity of Ccbe1 antibody (MBS3210856)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
RGAPGPPGSP GPPGSFDFLL LVLADIRNDI AELQEKVFGH RTHSSAEDFP
3D Structure
ModBase 3D Structure for Q3MI99
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of Ccbe1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Ccbe1 blocking peptide
This is a synthetic peptide designed for use in combination with anti-Ccbe1 Antibody, made
Target Description: Ccbe1 is required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis.
Product Categories/Family for Ccbe1 blocking peptide
Peptide
Applications Tested/Suitable for Ccbe1 blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for Ccbe1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_848908
[Other Products]
NCBI GenBank Nucleotide #
NM_178793
[Other Products]
UniProt Primary Accession #
Q3MI99
[Other Products]
UniProt Related Accession #
Q3MI99[Other Products]
NCBI Official Full Name
collagen and calcium-binding EGF domain-containing protein 1
NCBI Official Synonym Full Names
collagen and calcium binding EGF domains 1
NCBI Official Symbol
Ccbe1 [Similar Products]
NCBI Official Synonym Symbols
mKIAA1983; 4933426F18Rik; 9430093N24Rik
[Similar Products]
NCBI Protein Information
collagen and calcium-binding EGF domain-containing protein 1
UniProt Protein Name
Collagen and calcium-binding EGF domain-containing protein 1
UniProt Synonym Protein Names
Full of fluid protein homolog
Protein Family
Collagen and calcium-binding EGF domain-containing protein
UniProt Gene Name
Ccbe1 [Similar Products]
UniProt Synonym Gene Names
Kiaa1983 [Similar Products]
UniProt Entry Name
CCBE1_MOUSE
UniProt Comments for Ccbe1
CCBE1: Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis. Defects in CCBE1 are the cause of Hennekam lymphangiectasia-lymphedema syndrome (HLLS). HLLS is a generalized lymph-vessels dysplasia characterized by intestinal lymphangiectasia with severe lymphedema of the limbs, genitalia and face. In addition, affected individuals have unusual facies and severe mental retardation. Belongs to the CCBE1 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Cellular Component: proteinaceous extracellular matrix; extracellular space; collagen; extracellular region
Molecular Function: collagen binding; protease binding; calcium ion binding
Biological Process: positive regulation of angiogenesis; multicellular organismal development; lymphangiogenesis; angiogenesis
Research Articles on Ccbe1
1. Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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