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glucosidase, beta (bile acid) 2, ELISA Kit

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产品名称: glucosidase, beta (bile acid) 2, ELISA Kit
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简单介绍

glucosidase, beta (bile acid) 2, ELISA Kit


glucosidase, beta (bile acid) 2, ELISA Kit  的详细介绍
Product Name

glucosidase, beta (bile acid) 2 (GBA2), ELISA Kit

Full Product Name

Mouse Non-lysosomal glucosylceramidase, GBA2 ELISA Kit

Product Synonym Names
Mouse Non-lysosomal glucosylceramidase (GBA2) ELISA kit; AD035; DKFZp762K054; KIAA1605; MGC16895; bile acid beta-glucosidase; non-lysosomal glucosylceramidase; glucosidase; beta (bile acid) 2
Product Gene Name

GBA2 elisa kit

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Request for Current Manual Insert
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3D Structure
ModBase 3D Structure for Q69ZF3
Species Reactivity
Mouse
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of GBA2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for GBA2 purchase
MBS9327544 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the glucosidase, beta (bile acid) 2 (GBA2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GBA2. The ELISA analytical biochemical technique of the MBS9327544 kit is based on GBA2 antibody-GBA2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GBA2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GBA2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for GBA2. It may not necessarily be applicable to this product.
NCBI GI #
240120073
NCBI GeneID
230101
NCBI Accession #
NP_766280.2 [Other Products]
NCBI GenBank Nucleotide #
NM_172692.3 [Other Products]
UniProt Primary Accession #
Q69ZF3 [Other Products]
UniProt Secondary Accession #
Q6PGM3; Q8BTN9[Other Products]
UniProt Related Accession #
Q69ZF3[Other Products]
Molecular Weight
103,294 Da
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NCBI Official Full Name
non-lysosomal glucosylceramidase
NCBI Official Synonym Full Names
glucosidase beta 2
NCBI Official Symbol
Gba2  [Similar Products]
NCBI Official Synonym Symbols
F630034E04
  [Similar Products]
NCBI Protein Information
non-lysosomal glucosylceramidase; NLGase; bile acid; beta-glucosidase 2; glucosylceramidase 2; beta-glucocerebrosidase 2; glucosidase, beta (bile acid) 2
UniProt Protein Name
Non-lysosomal glucosylceramidase
UniProt Synonym Protein Names
Beta-glucocerebrosidase 2; Beta-glucosidase 2; Glucosylceramidase 2
UniProt Gene Name
Gba2  [Similar Products]
UniProt Synonym Gene Names
Kiaa1605; NLGase; Beta-glucosidase 2  [Similar Products]
UniProt Entry Name
GBA2_MOUSE
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UniProt Comments for GBA2
GBA2: Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O- glucosides, however, the relevance of such activity is unclear in vivo. Belongs to the non-lysosomal glucosylceramidase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; EC 3.2.1.45; Endoplasmic reticulum; Hydrolase

Cellular Component: Golgi apparatus; membrane; endoplasmic reticulum; integral to membrane

Molecular Function: beta-glucosidase activity; hydrolase activity; hydrolase activity, acting on glycosyl bonds; catalytic activity; glucosylceramidase activity

Biological Process: glucosylceramide catabolic process; sphingolipid metabolic process; glycoside catabolic process; bile acid metabolic process; metabolic process; lipid metabolic process; central nervous system neuron development
Research Articles on GBA2
1. the deletion of Gba2 significantly rescues the type 1 Gaucher disease clinical phenotype.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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