Full Product Name
SGCG Antibody
Product Gene Name
anti-SGCG antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q13326
Other Notes
Small volumes of anti-SGCG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for SGCG. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000222.1
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NCBI GenBank Nucleotide #
NM_000231.2
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UniProt Primary Accession #
Q13326
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UniProt Secondary Accession #
Q32M32; Q5T9J6[Other Products]
UniProt Related Accession #
Q13326[Other Products]
Molecular Weight
32,379 Da
NCBI Official Full Name
gamma-sarcoglycan
NCBI Official Synonym Full Names
sarcoglycan gamma
NCBI Official Symbol
SGCG [Similar Products]
NCBI Official Synonym Symbols
A4; MAM; DMDA; SCG3; 35DAG; DAGA4; DMDA1; LGMD2C; SCARMD2; gamma-SG
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NCBI Protein Information
gamma-sarcoglycan
UniProt Protein Name
Gamma-sarcoglycan
UniProt Synonym Protein Names
35 kDa dystrophin-associated glycoprotein; 35DAG
Protein Family
Gamma-sarcoglycan
UniProt Gene Name
SGCG [Similar Products]
UniProt Synonym Gene Names
Gamma-SG; 35DAG [Similar Products]
NCBI Summary for SGCG
This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008]
UniProt Comments for SGCG
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Research Articles on SGCG
1. This study showed that fifteen families were shown to carry SGCG variants in patient with early onset severe muscular dystrophy.
Precautions
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Disclaimer
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