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CLTR2, Polyclonal Antibody

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产品名称: CLTR2, Polyclonal Antibody
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简单介绍

CLTR2, Polyclonal Antibody


CLTR2, Polyclonal Antibody  的详细介绍
Product Name

CLTR2, Polyclonal Antibody

Full Product Name

CLTR2 antibody

Product Synonym Names
Polyclonal CLTR2; Anti-CLTR2; CysLTR2; Cysteinyl leukotriene receptor 2; HG57; HPN321; hGPCR21
Product Gene Name

anti-CLTR2 antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Specificity
CLTR2 antibody detects endogenous levels of total CLTR2 protein
Form/Format
Purified IgG in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/ml (lot specific)
Biological Significance
CLTR2 is a cysteinyl leukotrienes receptor.
Immunogen
CLTR2 antibody was raised in Rabbit using a synthesized peptide derived from internal of human CLTR2 as the immunogen
Preparation and Storage
Store at -20 degree C in small aliquots. Avoid repeated freeze-thaw cycles
Other Notes
Small volumes of anti-CLTR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-CLTR2 antibody
Rabbit polyclonal CLTR2 antibody
Product Categories/Family for anti-CLTR2 antibody
Signal Transduction; Purified Polyclonal Antibodies
Applications Tested/Suitable for anti-CLTR2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CLTR2 antibody
WB: 1:500-1:1000
ELISA: 1:5000

Western Blot (WB) of anti-CLTR2 antibody
Western blot analysis of extracts from HeLa cells and COLO cells using CLTR2 antibody
anti-CLTR2 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for CLTR2. It may not necessarily be applicable to this product.
NCBI GI #
242397436
NCBI GeneID
70086
NCBI Accession #
NP_001155884.1 [Other Products]
NCBI GenBank Nucleotide #
NM_001162412.1 [Other Products]
UniProt Secondary Accession #
A2RT90[Other Products]
UniProt Related Accession #
Q920A1[Other Products]
Molecular Weight
35,213 Da
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NCBI Official Full Name
cysteinyl leukotriene receptor 2
NCBI Official Synonym Full Names
cysteinyl leukotriene receptor 2
NCBI Official Symbol
Cysltr2  [Similar Products]
NCBI Official Synonym Symbols
Cltr2; Cyslt2; CYSLT2R; 2300001H05Rik
  [Similar Products]
NCBI Protein Information
cysteinyl leukotriene receptor 2
UniProt Protein Name
Cysteinyl leukotriene receptor 2
UniProt Gene Name
Cysltr2  [Similar Products]
UniProt Synonym Gene Names
Cyslt2; CysLTR2  [Similar Products]
UniProt Entry Name
CLTR2_MOUSE
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UniProt Comments for CLTR2
CYSLTR2: Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1

Cellular Component: membrane; integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; signal transducer activity; cysteinyl leukotriene receptor activity; leukotriene receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of angiogenesis; signal transduction
Research Articles on CLTR2
1. It plays a critical role in Ab1e42-induced neurotoxicity.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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