Cardiotrophin Like Cytokine Factor 1 (CLCF1), CLIA Kit

CLC; NR6; BSF3; CISS2; NNT1; Novel Neurotrophin-1; B Cell-Stimulating Factor-3

For Research Use Only. Not for use in diagnostic procedures.

This assay has high sensitivity and excellent specificity for detection of Cardiotrophin Like Cytokine Factor 1 (CLCF1).
No significant cross-reactivity or interference between Cardiotrophin Like Cytokine Factor 1 (CLCF1) and analogues was observed.

The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.

Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of CLCF1 clia kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

The microplate provided in this kit has been pre-coated with an antibody specific to Cardiotrophin Like Cytokine Factor 1 (CLCF1). Standards or samples are then added to the appropriate microplate wells with a biotin-conjugated antibody specific to Cardiotrophin Like Cytokine Factor 1 (CLCF1). Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then the mixture of substrate A and B is added to generate glow light emission kinetics. Upon plate development, the intensity of the emitted light is proportional to the Cardiotrophin Like Cytokine Factor 1 (CLCF1) level in the sample or standard.;

Cytokine; Cardiovascular biology; Neuroscience

25,261 Da

cardiotrophin-like cytokine factor 1

cardiotrophin-like cytokine factor 1

Cardiotrophin-like cytokine factor 1

Bsf3; Nnt1; BSF-3; NNT-1  [Similar Products]

CLCF1_MOUSE

CLCF1: Cytokine with B-cell stimulating capability. Binds to and activates the ILST/gp130 receptor. Defects in CLCF1 are the cause of cold-induced sweating syndrome type 2 (CISS2). Cold-induced sweating syndrome (CISS) is an autosomal recessive disorder characterized by profuse sweating induced by cool surroundings (temperatures of 7 to 18 degrees Celsius). Additional abnormalities include a high- arched palate, nasal voice, depressed nasal bridge, inability to fully extend the elbows and kyphoscoliosis. Belongs to the IL-6 superfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Apoptosis; Secreted, signal peptide; Cytokine

Cellular Component: extracellular space; extracellular region; intracellular

Molecular Function: protein binding; protein heterodimerization activity; cytokine activity; ciliary neurotrophic factor receptor binding; receptor binding

Biological Process: positive regulation of T-helper 2 type immune response; regulation of protein kinase B signaling cascade; JAK-STAT cascade; positive regulation of isotype switching to IgE isotypes; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of corticotropin-releasing hormone secretion; positive regulation of immunoglobulin production; cell surface receptor linked signal transduction; B cell differentiation; regulation of inflammatory response; positive regulation of cell proliferation; positive regulation of B cell proliferation; negative regulation of neuron apoptosis; positive regulation of astrocyte differentiation

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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.