Product Name
ADAMTS-like protein 4 (ADAMTSL4), ELISA Kit
Full Product Name
Porcine ADAMTS-like protein 4 (ADAMTSL4) ELISA Kit
Product Gene Name
ADAMTSL4 elisa kit
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
Species Reactivity
Porcine
Samples
Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
Preparation and Storage
Store all reagents at 2-8 degree C.
Sample Preparation
We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of ADAMTSL4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for ADAMTSL4 purchase
MBS7209464 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ADAMTS-like protein 4 (ADAMTSL4) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ADAMTSL4. The ELISA analytical biochemical technique of the MBS7209464 kit is based on ADAMTSL4 antibody-ADAMTSL4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ADAMTSL4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ADAMTSL4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Product Categories/Family for ADAMTSL4 elisa kit
Signal Transduction
NCBI/Uniprot data below describe general gene information for ADAMTSL4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001275537.1
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NCBI GenBank Nucleotide #
NM_001288608.1
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UniProt Secondary Accession #
Q5T5F7; Q6IPM6; Q8N643; Q9HBS6; B2RTT0; F8WAD0[Other Products]
UniProt Related Accession #
Q6UY14[Other Products]
Molecular Weight
118,822 Da
NCBI Official Full Name
ADAMTS-like protein 4 isoform 4
NCBI Official Synonym Full Names
ADAMTS-like 4
NCBI Official Symbol
ADAMTSL4 [Similar Products]
NCBI Official Synonym Symbols
TSRC1; ECTOL2; ADAMTSL-4
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NCBI Protein Information
ADAMTS-like protein 4; thrombospondin repeat-containing protein 1
UniProt Protein Name
ADAMTS-like protein 4
UniProt Synonym Protein Names
Thrombospondin repeat-containing protein 1
Protein Family
ADAMTS-like protein
UniProt Gene Name
ADAMTSL4 [Similar Products]
UniProt Synonym Gene Names
TSRC1; PP1396; UNQ2803/PRO34012; ADAMTSL-4 [Similar Products]
UniProt Entry Name
ATL4_HUMAN
NCBI Summary for ADAMTSL4
This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Sep 2014]
UniProt Comments for ADAMTSL4
TSRC1: Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis. Defects in ADAMTSL4 are a cause of autosomal recessive isolated ectopia lentis (ARI-EL). ARI-EL is a rare condition characterized by partial or complete displacement of the lens from its space resulting from defective zonule formation. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 1q21.3
Cellular Component: endoplasmic reticulum lumen
Molecular Function: protein binding; protease binding; metalloendopeptidase activity
Biological Process: protein amino acid O-linked glycosylation; extracellular matrix organization and biogenesis; cellular protein metabolic process; apoptosis; positive regulation of apoptosis; proteolysis; post-translational protein modification
Disease: Ectopia Lentis Et Pupillae; Ectopia Lentis 2, Isolated, Autosomal Recessive
Research Articles on ADAMTSL4
1. We have confirmed the gene and protein expression of ADAMTSL4 in human ocular tissue. The pattern of expression may suggest further functions of this gene beyond those suggested by its causative role in isolated ectopia lentis.
Precautions
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Disclaimer
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