G protein-coupled receptor 56, ELISA Kit

Human G-protein coupled receptor 56 (GPR56) ELISA kit; BFPP; DKFZp781L1398; TM7LN4; TM7XN1; 7-transmembrane protein with no EGF-like N-terminal domains-1; EGF-TM7-like; G protein-coupled receptor 56

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of GPR56 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9331082 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the G protein-coupled receptor 56 (GPR56) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GPR56. The ELISA analytical biochemical technique of the MBS9331082 kit is based on GPR56 antibody-GPR56 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GPR56 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GPR56. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

77,738 Da

G protein-coupled receptor 56

G-protein coupled receptor 56; 7-transmembrane protein with no EGF-like N-terminal domains-1

G-protein coupled receptor 56

TM7LN4; TM7XN1; UNQ540/PRO1083; GPR56 NT; GPR56(N); GPR56 CT; GPR56(C); GPR56 7TM  [Similar Products]

GPR56_HUMAN

This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

GPR56: Could be involved in cell-cell interactions. Defects in GPR56 are the cause of bilateral frontoparietal polymicrogyria (BFPP). BFPP is characterized by disorganized cortical lamination that is most severe in frontal cortex. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; GPCR, family 2; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16q21

Cellular Component: integral to plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; collagen binding; extracellular matrix binding

Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of cell proliferation; positive regulation of cell adhesion; cell-cell signaling; cerebral cortex radial glia guided migration; positive regulation of Rho protein signal transduction; brain development; angiogenesis; cell adhesion; layer formation in the cerebral cortex; Rho protein signal transduction

Disease: Polymicrogyria, Bilateral Frontoparietal; Polymicrogyria, Bilateral Perisylvian, Autosomal Recessive

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.