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ES cell expressed Ras, ELISA Kit

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产品名称: ES cell expressed Ras, ELISA Kit
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简单介绍

ES cell expressed Ras, ELISA Kit


ES cell expressed Ras, ELISA Kit  的详细介绍
Product Name

ES cell expressed Ras (ERAS), ELISA Kit

Full Product Name

Human GTPase ERas, ERAS ELISA Kit

Product Synonym Names
Human GTPase ERas (ERAS) ELISA kit; HRAS2; HRASP; MGC126691; MGC126693; small GTPase protein E-Ras; v-Ha-ras Harvey rat sarcoma viral oncogene homolog 2; v-Ha-ras Harvey rat sarcoma viral oncogene homolog pseudogene; ES cell expressed Ras
Product Gene Name

ERAS elisa kit

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Request for Current Manual Insert
Request Current Manual
OMIM
300437
3D Structure
ModBase 3D Structure for Q7Z444
Species Reactivity
Human
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of ERAS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for ERAS purchase
MBS9340905 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ES cell expressed Ras (ERAS) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ERAS. The ELISA analytical biochemical technique of the MBS9340905 kit is based on ERAS antibody-ERAS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ERAS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ERAS. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ERAS. It may not necessarily be applicable to this product.
NCBI GI #
31559833
NCBI GeneID
3266
NCBI Accession #
NP_853510.1 [Other Products]
NCBI GenBank Nucleotide #
NM_181532.3 [Other Products]
UniProt Primary Accession #
Q7Z444 [Other Products]
UniProt Related Accession #
Q7Z444[Other Products]
Molecular Weight
25,287 Da
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NCBI Official Full Name
GTPase ERas
NCBI Official Synonym Full Names
ES cell expressed Ras
NCBI Official Symbol
ERAS  [Similar Products]
NCBI Official Synonym Symbols
HRAS2; HRASP
  [Similar Products]
NCBI Protein Information
GTPase ERas; E-Ras; small GTPase protein E-Ras; embryonic stem cell-expressed Ras; v-Ha-ras Harvey rat sarcoma viral oncogene homolog 2; v-Ha-ras Harvey rat sarcoma viral oncogene homolog pseudogene
UniProt Protein Name
GTPase ERas
UniProt Synonym Protein Names
Embryonic stem cell-expressed Ras
Protein Family
GTPase
UniProt Gene Name
ERAS  [Similar Products]
UniProt Synonym Gene Names
HRAS2; HRASP; E-Ras  [Similar Products]
UniProt Entry Name
RASE_HUMAN
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NCBI Summary for ERAS
This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012]
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UniProt Comments for ERAS
ERas: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells. Belongs to the small GTPase superfamily. Ras family.

Protein type: G protein, monomeric, Ras; G protein; G protein, monomeric

Chromosomal Location of Human Ortholog: Xp11.23

Cellular Component: plasma membrane

Molecular Function: GTP binding

Biological Process: small GTPase mediated signal transduction
Research Articles on ERAS
1. After knocking down the ERas gene by siRNA, we observed that there was a significant decrease in proliferation, metastasis as well as clonality in gastric carcinoma.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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