Product Name
RAB40A/L, Polyclonal Antibody
Full Product Name
RAB40A/L Antibody
Product Synonym Names
Ras-related protein Rab-40A-like
Product Gene Name
anti-RAB40A/L antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P0C0E4
Specificity
RAB40A/L Antibody detects endogenous levels of total RAB40A/L
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (lot specific)
Immunogen
A synthesized peptide derived from human RAB40A/L
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-RAB40A/L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-RAB40A/L antibody
Total protein Ab
Applications Tested/Suitable for anti-RAB40A/L antibody
Western Blot (WB)
Application Notes for anti-RAB40A/L antibody
Western Blot: 1:1000-3000
Western Blot (WB) of anti-RAB40A/L antibody
Western blot analysis RAB40A/L using HeLa whole cell lysates
NCBI/Uniprot data below describe general gene information for RAB40A/L. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001027004.1
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NCBI GenBank Nucleotide #
NM_001031834.1
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UniProt Primary Accession #
P0C0E4
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UniProt Secondary Accession #
Q495H3[Other Products]
UniProt Related Accession #
P0C0E4[Other Products]
Molecular Weight
31,239 Da
NCBI Official Full Name
ras-related protein Rab-40A-like
NCBI Official Synonym Full Names
RAB40A, member RAS oncogene family-like
NCBI Official Symbol
RAB40AL [Similar Products]
NCBI Official Synonym Symbols
RAR2; RLGP; MRXSMP
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NCBI Protein Information
ras-related protein Rab-40A-like
UniProt Protein Name
Ras-related protein Rab-40A-like
UniProt Synonym Protein Names
Ras-like GTPase
UniProt Gene Name
RAB40AL [Similar Products]
UniProt Synonym Gene Names
RLGP [Similar Products]
UniProt Entry Name
RB40L_HUMAN
NCBI Summary for RAB40A/L
This gene encodes a member of the Rab40 subfamily of Rab small GTP-binding proteins that contains a C-terminal suppressors of cytokine signaling box. Disruptions in this gene are associated with Duchenne muscular dystrophy. [provided by RefSeq, Apr 2010]
UniProt Comments for RAB40A/L
RAB40AL: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Belongs to the small GTPase superfamily. Rab family.
Protein type: G protein; G protein, monomeric; G protein, monomeric, Rab; Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: Xq22.2
Cellular Component: cytoplasm; mitochondrion
Disease: Mental Retardation, X-linked, Syndromic, Martin-probst Type
Research Articles on RAB40A/L
1. Our findings are inconsistent with a causative effect of RAB40AL p.D59G on cognitive impairment combined with severe to profound bilateral hearing loss but indicate that p.D59G is a common genetic variation.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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