Product Name
Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1a), Antibody Pair Kit
Full Product Name
Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1a) Antibody Pair Kit (with Standard)
Product Synonym Names
ENaCa; ENaCalpha; SCNEA; SCNN1; Sodium Channel,Nonvoltage-Gated 1,Alpha; Epithelial Na(+) channel subunit alpha; Nonvoltage-gated sodium channel 1 subunit alpha
Product Gene Name
SCNN1a antibody pair kit
[Similar Products]
Matching Pairs
Antibody: Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1a) (MBS2102444)
Pairing: Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1a) (MBS2102444)
Comments: Matched antibody pair kit containing antibody/standard combination
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for P37089
Samples
Serum, Plasma, Tissue Homogenates and Other Biological Fluids
Detection Range
0.312-20ng/mL
Standard
Recombinant SCNN1a (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customerâs specifications, please inquire.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of SCNN1a antibody pair kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for SCNN1a antibody pair kit
Signal transduction;
Applications Tested/Suitable for SCNN1a antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
NCBI/Uniprot data below describe general gene information for SCNN1a. It may not necessarily be applicable to this product.
NCBI Accession #
NP_113736.1
[Other Products]
NCBI GenBank Nucleotide #
NM_031548.2
[Other Products]
UniProt Primary Accession #
P37089
[Other Products]
UniProt Secondary Accession #
Q64593; Q9QUI4[Other Products]
UniProt Related Accession #
P37089[Other Products]
Molecular Weight
78,888 Da
NCBI Official Full Name
amiloride-sensitive sodium channel subunit alpha
NCBI Official Synonym Full Names
sodium channel epithelial 1 alpha subunit
NCBI Official Symbol
Scnn1a [Similar Products]
NCBI Official Synonym Symbols
ENaCA
[Similar Products]
NCBI Protein Information
amiloride-sensitive sodium channel subunit alpha
UniProt Protein Name
Amiloride-sensitive sodium channel subunit alpha
UniProt Synonym Protein Names
Alpha-NaCH; Epithelial Na(+) channel subunit alpha; Alpha-ENaC; Nonvoltage-gated sodium channel 1 subunit alpha; SCNEA
Protein Family
Amiloride-sensitive sodium channel
UniProt Gene Name
Scnn1a [Similar Products]
UniProt Synonym Gene Names
Renac; Alpha-ENaC [Similar Products]
NCBI Summary for SCNN1a
acts as an epithelial sodium ion channel; regulates salt and fluid transport in the kidney [RGD, Feb 2006]
UniProt Comments for SCNN1a
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells (PubMed:8382172). Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and eccrine sweat glands. Also plays a role in taste perception ().
Research Articles on SCNN1a
1. Studied the effect and underlining mechanisms of MaR1(maresin 1) in modulating alveolar fluid clearance on LPS-induced acute lung injury; found MaR1 improved epithelial sodium channel (ENaC) and Na,K-adenosine triphosphatase expression and activity.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.