Product Name
Intraflagellar transport protein 122 homolog (Ift122), Recombinant Protein
Full Product Name
Recombinant Mouse Intraflagellar transport protein 122 homolog (Ift122) , partial
Product Gene Name
Ift122 recombinant protein
[Similar Products]
Product Synonym Gene Name
Ift122[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q6NWV3
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Ift122 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Ift122 recombinant protein
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
NCBI/Uniprot data below describe general gene information for Ift122. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001161235.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001167763.1
[Other Products]
UniProt Primary Accession #
Q6NWV3
[Other Products]
UniProt Secondary Accession #
Q6KAU2; Q8C8U5; Q8CD77[Other Products]
UniProt Related Accession #
Q6NWV3[Other Products]
Molecular Weight
134,869 Da
NCBI Official Full Name
intraflagellar transport protein 122 homolog isoform 2
NCBI Official Synonym Full Names
intraflagellar transport 122
NCBI Official Symbol
Ift122 [Similar Products]
NCBI Official Synonym Symbols
sopb; Wdr10; C86139
[Similar Products]
NCBI Protein Information
intraflagellar transport protein 122 homolog
UniProt Protein Name
Intraflagellar transport protein 122 homolog
UniProt Synonym Protein Names
WD repeat-containing protein 10
Protein Family
Intraflagellar transport protein
UniProt Gene Name
Ift122 [Similar Products]
UniProt Synonym Gene Names
Wdr10 [Similar Products]
UniProt Comments for Ift122
Required for cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia.
Research Articles on Ift122
1. Data show that IFT122 controls the ciliary localization of Shh pathway regulators in different ways.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.