B4GALT7, Polyclonal Antibody

B4GAL T7; Beta 1, 4 galactosyltransferase 7; Beta 1, 4 GalTase 7; Beta4Gal T7; UDP Gal:beta GlcNAc beta 1, 4 galactosyltransferase 7; XGALT 1; XGALT1; XGPT1; Xylosylprotein beta 1, 4 galactosyltransferase, polypeptide 7

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

B4GALT7 antibody detects endogenous levels of total B4GALT7

The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.

Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

1mg/ml (lot specific)

Store at -20 degree C. Stable for 12 months from date of receipt.

Manufactured in an ISO 9001:2015 Certified Laboratory.

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Small volumes of anti-B4GALT7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Function: Required for the biosynthesis of the tetrasaccharide linkage region of proteoglycans, especially for small proteoglycans in skin fibroblasts.
Similarity: Belongs to the glycosyltransferase 7 family.

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

WB: 1:1000-3000
IHC: 1:200

Western blot analysis of B4GALT7 using A549 whole cell lysates

MBS9609593 at 1/100 staining Human brain cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.

Observed: 37 kDa
Predicted: 38 kDa

beta-1,4-galactosyltransferase 7

beta-1,4-galactosyltransferase 7

Beta-1,4-galactosyltransferase 7

XGALT1; Beta-1,4-GalTase 7; Beta4Gal-T7; b4Gal-T7  [Similar Products]

This gene is a member of the beta-1,4-galactosyltransferase (beta4GalT) family. Family members encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose. Each beta4GalT member has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus which then remains uncleaved to function as a transmembrane anchor. The enzyme encoded by this gene attaches the first galactose in the common carbohydrate-protein linkage (GlcA-beta1,3-Gal-beta1,3-Gal-beta1,4-Xyl-beta1-O-Ser) found in proteoglycans. This enzyme differs from other beta4GalTs because it lacks the conserved Cys residues found in beta4GalT1-beta4GalT6 and it is located in cis-Golgi instead of trans-Golgi. Mutations in this gene have been associated with the progeroid form of Ehlers-Danlos syndrome. [provided by RefSeq, Oct 2009]

Required for the biosynthesis of the tetrasaccharide linkage region of proteoglycans, especially for small proteoglycans in skin fibroblasts.

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