Full Product Name
SNAP29 Antibody
Product Gene Name
anti-SNAP29 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O95721
Other Notes
Small volumes of anti-SNAP29 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for SNAP29. It may not necessarily be applicable to this product.
NCBI Accession #
NP_004773.1
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NCBI GenBank Nucleotide #
NM_004782.3
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UniProt Primary Accession #
O95721
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UniProt Related Accession #
O95721[Other Products]
Molecular Weight
28,970 Da
NCBI Official Full Name
synaptosomal-associated protein 29
NCBI Official Synonym Full Names
synaptosome associated protein 29
NCBI Official Symbol
SNAP29 [Similar Products]
NCBI Official Synonym Symbols
CEDNIK; SNAP-29
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NCBI Protein Information
synaptosomal-associated protein 29
UniProt Protein Name
Synaptosomal-associated protein 29
UniProt Synonym Protein Names
Soluble 29 kDa NSF attachment protein
Protein Family
SNAP25 homologous protein
UniProt Gene Name
SNAP29 [Similar Products]
UniProt Synonym Gene Names
SNAP-29 [Similar Products]
NCBI Summary for SNAP29
This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for SNAP29
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Plays also a role in ciliogenesis by regulating membrane fusions.
Research Articles on SNAP29
1. NEK3 kinase phosphorylates SNAP29 on its serine 105. NEK3-mediated phosphorylation determines membrane localization of SNAP29. Membrane-associated SNAP29 regulates Golgi and focal adhesion structures.
Precautions
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Disclaimer
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