Product Name
C19orf50 (KXD1), Polyclonal Antibody
Popular Item
Full Product Name
C19orf50 Antibody (Center)
Product Synonym Names
KxDL motif-containing protein 1; KXD1; C19orf50
Product Gene Name
anti-KXD1 antibody
[Similar Products]
Antibody/Peptide Pairs
C19orf50 peptide (MBS9228038) is used for blocking the activity of C19orf50 antibody (MBS9201761)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Positions
59-85
3D Structure
ModBase 3D Structure for Q9BQD3
Species Reactivity
Human (Predicted Reactivity: Bovine, Mouse, Rat)
Specificity
This C19orf50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-85 amino acids from the Central region of human C19orf50.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (lot specific)
Antigen Type
Synthetic Peptide
Function
As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167). May be involved in the biogenesis of lysosome-related organelles such as melanosomes (By similarity).
Cellular Location
Lysosome membrane
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-KXD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-KXD1 antibody
The function of the C19orf50 protein has not yet been determined.
Product Categories/Family for anti-KXD1 antibody
Cell Biology
Applications Tested/Suitable for anti-KXD1 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P)
Application Notes for anti-KXD1 antibody
WB~~1:1000
IHC-P~~1:50~100
Western Blot (WB) of anti-KXD1 antibody
C19orf50 Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the C19orf50 antibody detected the C19orf50 protein (arrow).
Immunohistochemistry (IHC) of anti-KXD1 antibody
C19orf50 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the C19orf50 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Western Blot (WB) of anti-KXD1 antibody
Western blot analysis of C19orf50 (arrow) using rabbit polyclonal C19orf50 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the C19orf50 gene.
NCBI/Uniprot data below describe general gene information for KXD1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001165419.1
[Other Products]
NCBI Related Accession #
Human (Predicted Reactivity: Bovine, Mouse, Rat)NP_001165420.1; NP_076974.2[Other Products]
NCBI GenBank Nucleotide #
NM_001171948.1
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UniProt Primary Accession #
Q9BQD3
[Other Products]
UniProt Secondary Accession #
O76098[Other Products]
UniProt Related Accession #
Q9BQD3[Other Products]
NCBI Official Full Name
kxDL motif-containing protein 1
NCBI Official Synonym Full Names
KxDL motif containing 1
NCBI Official Symbol
KXD1 [Similar Products]
NCBI Official Synonym Symbols
KXDL; MST096; MSTP096; C19orf50
[Similar Products]
NCBI Protein Information
kxDL motif-containing protein 1
UniProt Protein Name
KxDL motif-containing protein 1
Protein Family
KxDL motif-containing protein
UniProt Gene Name
KXD1 [Similar Products]
UniProt Synonym Gene Names
C19orf50 [Similar Products]
UniProt Entry Name
KXDL1_HUMAN
UniProt Comments for KXD1
KXD1: protein of unknown function.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 19p13.11
Molecular Function: protein binding
Biological Process: vesicle-mediated transport
Product References and Citations for anti-KXD1 antibody
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Research Articles on KXD1
1. KXD1 interacts with BLOS1.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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