Acidic mammalian chitinase, ELISA Kit

Acidic mammalian chitinase; AMCase; YNL; Chia; 3.2.1.14; Chia1

For Research Use Only. Not for use in diagnostic procedures.

Store at 4 degree C

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Small volumes of Chia elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9428718 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Acidic mammalian chitinase (Chia) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Chia. The ELISA analytical biochemical technique of the MBS9428718 kit is based on Chia antibody-Chia antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Chia antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Chia. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

52,003 Da

chitinase, acidic 1

acidic mammalian chitinase

Acidic mammalian chitinase

Chia1; AMCase  [Similar Products]

CHIA: Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding. Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Carbohydrate Metabolism - amino sugar and nucleotide sugar; EC 3.2.1.14; Hydrolase; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3|3 F2.2

Cellular Component: cytoplasm; extracellular region; extracellular space

Molecular Function: chitin binding; chitinase activity; kinase binding

Biological Process: chitin catabolic process; production of molecular mediator of acute inflammatory response

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