Full Product Name
CXG2 Antibody
Product Synonym Names
connexin-46.6; connexin-47; Cx46.6; Cx47; CXG2; gap junction alpha-12
Product Gene Name
anti-CXG2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q5T442
Specificity
CXG2 Antibody detects endogenous levels of total CXG2
Purity/Purification
Immunogen affinity purified
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
A synthesized peptide
Preparation and Storage
Store at-20 degree C. Stable for 12 months from date of receipt.
Other Notes
Small volumes of anti-CXG2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CXG2 antibody
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes for anti-CXG2 antibody
WB: 1:500~1:1000
IF/ICC: 1:100-1:500
NCBI/Uniprot data below describe general gene information for CXG2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_065168.2
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NCBI GenBank Nucleotide #
NM_020435.3
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UniProt Primary Accession #
Q5T442
[Other Products]
UniProt Secondary Accession #
O43440; Q7Z7J2; Q8IWJ9[Other Products]
UniProt Related Accession #
Q5T442[Other Products]
NCBI Official Full Name
gap junction gamma-2 protein
NCBI Official Synonym Full Names
gap junction protein gamma 2
NCBI Official Symbol
GJC2 [Similar Products]
NCBI Official Synonym Symbols
Cx47; HLD2; GJA12; SPG44; CX46.6; LMPH1C; PMLDAR
[Similar Products]
NCBI Protein Information
gap junction gamma-2 protein
UniProt Protein Name
Gap junction gamma-2 protein
UniProt Synonym Protein Names
Connexin-46.6; Cx46.6; Connexin-47; Cx47; Gap junction alpha-12 protein
UniProt Gene Name
GJC2 [Similar Products]
UniProt Synonym Gene Names
GJA12; Cx46.6; Cx47 [Similar Products]
NCBI Summary for CXG2
This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1. [provided by RefSeq, Jul 2008]
UniProt Comments for CXG2
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a role in myelination in central and peripheral nervous systems.
Research Articles on CXG2
1. GJC2 promoter region mutation screening should be included in the evaluation of patients with unexplained hypomyelinating leukodystrophies.
Precautions
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Disclaimer
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